Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation

Saminathan, M.; Singh, K. P.; Vineetha, S.; Maity, Madhulina; Biswas, S. K.; Manjunathareddy, G. B.; Chauhan, H. C.; Milton, A. A. P.; Ramakrishnan, M. A.; Maan, Sushila; Maan, N. S.; Chandel, B. S.; Hemadri, D.; Gupta, V. K.; Mertens, P. P. C.

doi:10.1038/s41598-020-58268-0

All Outputs (5)

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells (2020)
Journal Article
Stokes, S., Almire, F., Tatham, M. H., McFarlane, S., Mertens, P., Pondeville, E., & Boutell, C. (2020). The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. PLoS Pathogens, 16(12), Article e1009134. https://doi.org/10.1371/journal.ppat.1009134

Mosquitoes are responsible for the transmission of many clinically important arboviruses that cause significant levels of annual mortality and socioeconomic health burden worldwide. Deciphering the mechanisms by which mosquitoes modulate arbovirus in... Read More about The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells.

Diversity of Transmission Outcomes Following Co-Infection of Sheep with Strains of Bluetongue Virus Serotype 1 and 8 (2020)
Journal Article
Veronesi, E., Darpel, K., Gubbins, S., Batten, C., Nomikou, K., Mertens, P., & Carpenter, S. (2020). Diversity of Transmission Outcomes Following Co-Infection of Sheep with Strains of Bluetongue Virus Serotype 1 and 8. Microorganisms, 8(6), Article 851. https://doi.org/10.3390/microorganisms8060851

Bluetongue virus (BTV) causes an economically important disease, bluetongue (BT), in susceptible ruminants and is transmitted primarily by species of Culicoides biting midges (Diptera: Ceratopogonidae). Since 2006, northern Europe has experienced mul... Read More about Diversity of Transmission Outcomes Following Co-Infection of Sheep with Strains of Bluetongue Virus Serotype 1 and 8.

Continuous Cell Lines from the European Biting Midge Culicoides nubeculosus (Meigen, 1830) (2020)
Journal Article
Bell-Sakyi, L., Mohd Jaafar, F., Monsion, B., Luu, L., Denison, E., Carpenter, S., …Mertens, P. P. C. (2020). Continuous Cell Lines from the European Biting Midge Culicoides nubeculosus (Meigen, 1830). Microorganisms, 8(6), Article 825. https://doi.org/10.3390/microorganisms8060825

Culicoides biting midges (Diptera: Ceratopogonidae) transmit arboviruses of veterinary or medical importance, including bluetongue virus (BTV) and Schmallenberg virus, as well as causing severe irritation to livestock and humans. Arthropod cell lines... Read More about Continuous Cell Lines from the European Biting Midge Culicoides nubeculosus (Meigen, 1830).

“Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence (2020)
Journal Article
Pascall, D. J., Nomikou, K., Bréard, E., Zientara, S., da Silva Filipe, A., Hoffmann, B., …Palmarini, M. (2020). “Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence. PLoS Biology, 18(4), Article e300067. https://doi.org/10.1371/journal.pbio.3000673

© 2020 Pascall et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cr... Read More about “Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence.

Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation (2020)
Journal Article
Saminathan, M., Singh, K. P., Vineetha, S., Maity, M., Biswas, S. K., Manjunathareddy, G. B., …Mertens, P. P. C. (2020). Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation. Scientific Reports, 10(1), Article 2164. https://doi.org/10.1038/s41598-020-58268-0

© 2020, The Author(s). Transplacental transmission (TPT) of wild-type Indian BTV-1 had never been experimentally proved. This study was first time investigated TPT of Indian BTV-1 (isolated from aborted and stillborn goat fetal spleens). The sequenti... Read More about Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation.