All Outputs (3)

Non?invasive measurement of retinal permeability in a diabetic rat model (2020)
Journal Article
Whatmore, J. L., Allen, C. L., Malhi, N. K., Whatmore, J. D., Bates, D. O., & Arkill, K. P. (2020). Non?invasive measurement of retinal permeability in a diabetic rat model. Microcirculation, 27(6), https://doi.org/10.1111/micc.12623

Objective: The gold standard for measuring blood-retinal barrier permeability is the Evans blue assay. However, this technique has limitations in vivo, including non-specific tissue binding and toxicity. This study describes a non-toxic, high through... Read More about Non?invasive measurement of retinal permeability in a diabetic rat model.

Mathematical model to determine the effect of a sub-glycocalyx space (2020)
Journal Article
Dyson, R. J., Dalwadi, M. P., Dalwadi, M. P., King, J. R., Dyson, R. J., & Arkill, K. P. (2020). Mathematical model to determine the effect of a sub-glycocalyx space. Physical Review Fluids, 5(4), https://doi.org/10.1103/physrevfluids.5.043103

We consider the drainage of blood plasma across the capillary wall, focusing on the flow through the endothelial glycocalyx layer that coats the luminal surface of vascular endothelial cells. We investigate how the presence of a sub-glycocalyx space... Read More about Mathematical model to determine the effect of a sub-glycocalyx space.

Local microvascular leakage promotes trafficking of activated neutrophils to remote organs (2020)
Journal Article
Owen-Woods, C., Joulia, R., Barkaway, A., Rolas, L., Ma, B., Nottebaum, A. F., …Nourshargh, S. (2020). Local microvascular leakage promotes trafficking of activated neutrophils to remote organs. Journal of Clinical Investigation, 130(5), 2301-2318. https://doi.org/10.1172/JCI133661

Copyright: © 2020, Owen-Woods et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License. Increased microvascular permeability to plasma proteins and neutrophil emigration are hallmar... Read More about Local microvascular leakage promotes trafficking of activated neutrophils to remote organs.