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All Outputs (6)

Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial (2020)
Journal Article
Korfage, I. J., Carreras, G., Arnfeldt Christensen, C. M., Billekens, P., Bramley, L., Briggs, L., …Rietjens, J. A. C. (2020). Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial. PLoS Medicine, 17(11), Article e1003422. https://doi.org/10.1371/journal.pmed.1003422

Background: Advance care planning (ACP) supportsindividuals to define, discuss, and record goals and preferences for future medical treatment and care. Despite being internationally recommended, randomized clinical trials of ACP in patients with adva... Read More about Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial.

Immediate versus delayed short-term integrated palliative care for advanced long-term neurological conditions: the OPTCARE Neuro RCT (2020)
Journal Article
Hepgul, N., Wilson, R., Yi, D., Evans, C., Bajwah, S., Crosby, V., …Gao, W. (2020). Immediate versus delayed short-term integrated palliative care for advanced long-term neurological conditions: the OPTCARE Neuro RCT. Health Services and Delivery Research, 8(36), 1-80. https://doi.org/10.3310/hsdr08360

Background Palliative care is recommended to help meet the needs of patients with progressive non-cancer conditions, such as long-term neurological conditions. However, few trials have tested palliative care in this population. Objectives To det... Read More about Immediate versus delayed short-term integrated palliative care for advanced long-term neurological conditions: the OPTCARE Neuro RCT.

Effect of short-term integrated palliative care on patient-reported outcomes among people with advanced long-term neurological conditions : A randomized clinical trial (2020)
Journal Article
Gao, W., Wilson, R., Hepgul, N., Yi, D., Evans, C., Bajwah, S., …Higginson, I. J. (2020). Effect of short-term integrated palliative care on patient-reported outcomes among people with advanced long-term neurological conditions : A randomized clinical trial. JAMA Network Open, 3(8), Article e2015061. https://doi.org/10.1001/jamanetworkopen.2020.15061

The relationship between ECOG-PS, mGPS, BMI/WL grade and body composition and physical function in patients with advanced cancer (2020)
Journal Article
Fallon, M., Dolan, R. D., Daly, L. E., Simmons, C. P. L., Wilcock, A., Usborne, C., …Maddocks, M. (2020). The relationship between ECOG-PS, mGPS, BMI/WL grade and body composition and physical function in patients with advanced cancer. Cancers, 12(5), Article 1187. https://doi.org/10.3390/cancers12051187

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Cancer remains one of the leading causes of mortality worldwide and the associated reduction in physical function has a marked impact on both quality of life and survival. The aim of the prese... Read More about The relationship between ECOG-PS, mGPS, BMI/WL grade and body composition and physical function in patients with advanced cancer.

Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility) (2020)
Journal Article
Higginson, I. J., Wilcock, A., Johnson, M. J., Bajwah, S., Lovell, N., Yi, D., …Brown, S. (2020). Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility). Thorax, 75(2), 176-179. https://doi.org/10.1136/thoraxjnl-2019-213879

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. New treatments are required for severe breathlessness in advanced disease. We conducted a randomised feasibility trial of mirtazapine over 28 days in adults with... Read More about Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility).