Skip to main content

Research Repository

Advanced Search

All Outputs (22)

Method for RNA extraction and transcriptomic analysis of single fungal spores (2019)
Journal Article
Geoghegan, I. A., Emes, R. D., Archer, D. B., & Avery, S. V. (2020). Method for RNA extraction and transcriptomic analysis of single fungal spores. MethodsX, 7, 50-55. https://doi.org/10.1016/j.mex.2019.12.002

Transcriptomic analysis of single cells has been increasingly in demand in recent years, thanks to technological and methodological advances as well as growing recognition of the importance of individuals in biological systems. However, the majority... Read More about Method for RNA extraction and transcriptomic analysis of single fungal spores.

Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo (2019)
Journal Article
Faidra Angelerou, M. G., Markus, R., Paraskevopoulou, V., Foralosso, R., Clarke, P., Alvarez, C. V., …Marlow, M. (2020). Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo. Journal of Controlled Release, 317, 118-129. https://doi.org/10.1016/j.jconrel.2019.10.011

Supramolecular gels have recently emerged as promising biomaterials for the delivery of a wide range of bioactive molecules, from small hydrophobic drugs to large biomolecules such as proteins. Although it has been demonstrated that each encapsulated... Read More about Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo.

Assessment of costs and insurance policies for referral treatment of equine colic (2019)
Journal Article
Barker, I., & Freeman, S. L. (2019). Assessment of costs and insurance policies for referral treatment of equine colic. Veterinary Record, 185(16), 1-6. https://doi.org/10.1136/vr.105415

Colic is the most common emergency problem in horses. The aims of this study were to survey costs of different referral treatments and to review insurance policies relevant to horses with colic. Data were collected retrospectively from nine equine ho... Read More about Assessment of costs and insurance policies for referral treatment of equine colic.

Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses (2019)
Journal Article
Habershon?Butcher, J., Cutler, C., Viljanto, M., Hincks, P. R., Biddle, S., & Paine, S. W. (2020). Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses. Journal of Veterinary Pharmacology and Therapeutics, 43(1), 6-12. https://doi.org/10.1111/jvp.12820

© 2019 John Wiley & Sons Ltd Xylazine is widely used worldwide as a short-acting sedative in general equine and racing practice. In the UK, although it has a legitimate use during training, equine anti-doping rules state it is a prohibited substanc... Read More about Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses.

Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition (2019)
Journal Article
Kletukhina, S., Neustroeva, O., James, V., Rizvanov, A., & Gomzikova, M. (2019). Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition. International Journal of Molecular Sciences, 20(19), https://doi.org/10.3390/ijms20194813

Epithelial-mesenchymal transition (EMT) is a process that takes place during embryonic development, wound healing, and under some pathological processes, including fibrosis and tumor progression. The molecular changes occurring within epithelial cell... Read More about Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition.

Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge (2019)
Journal Article
Clarkson, A., Paine, S., Martín-Tereso, J., & Kendall, N. (2020). Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge. Nutrition Research Reviews, 33(1), 43-49. https://doi.org/10.1017/S0954422419000180

Ruminants are recognised to suffer from Cu-responsive disorders. Present understanding of Cu transport and metabolism is limited and inconsistent across vets and veterinary professionals. There has been much progress from the studies of the 1980s and... Read More about Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge.

Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse (2019)
Journal Article
Bowden, A., Burford, J., Brennan, M., England, G., & Freeman, S. (2019). Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse. Equine Veterinary Journal, https://doi.org/10.1111/evj.13173

Background Colic is the most common emergency problem in the horse. An owner’s ability to recognise colic and seek assistance is a critical first step in determining case outcome. Objectives The aim of this study was to assess horse owners’ know... Read More about Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse.

Key concepts for making informed choices (2019)
Journal Article
Aronson, J. K., Barends, E., Boruch, R., Brennan, M., Chalmers, I., Chislett, J., …Vale, L. (2019). Key concepts for making informed choices. Nature, 572(7769), 303-306. https://doi.org/10.1038/d41586-019-02407-9

An alliance of researchers lays out a framework for taking decisions based on thinking critically about claims and comparisons. Everyone makes claims about what works. Politicians claim that stop and search will reduce violent crime; friends claim th... Read More about Key concepts for making informed choices.

Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica (2019)
Journal Article
Kletenkov, K., Martynova, E., Davidyuk, Y., Kabwe, E., Shamsutdinov, A., Garanina, E., …Morzunov, S. (2019). Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica. Viruses, 11(7), Article 675. https://doi.org/10.3390/v11070675

Nephropathia Epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) and linked to hantavirus infection, is endemic in the Republic of Tatarstan. Several genetic markers of HFRS severity have been identified previously, including... Read More about Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica.

The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro (2019)
Journal Article
Chen, D., Tian, A., Hou, J., Li, J., Tian, X., Yuan, X., …Zhu, X. (2019). The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro. Frontiers in Immunology, 10, Article 1707. https://doi.org/10.3389/fimmu.2019.01707

Cathepsin B, a lysosomal cysteine protease, is thought to be involved in the pathogenesis of Fasciola gigantica infection, but its exact role remains unclear. In the present study, a recombinant F. gigantica cathepsin B (rFgCatB) protein was expresse... Read More about The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro.

The future of cattle veterinary practice: insights from a qualitative study (2019)
Journal Article
Woodward, H., Cobb, K., & Remnant, J. (2019). The future of cattle veterinary practice: insights from a qualitative study. Veterinary Record, 185(7), https://doi.org/10.1136/vr.105321

The British livestock sector is constantly changing due to environmental and economic pressures, consequentially causing a shift in demand on farm veterinary services. The aim of this study was to explore the future of cattle veterinary practice, usi... Read More about The future of cattle veterinary practice: insights from a qualitative study.

Avian malaria-mediated population decline of a widespread iconic bird species (2019)
Journal Article
Dadum, D., Robinson, R., Clements, A., Peach, W., Bennett, M., Rowcliffe, J. M., & Cunningham, A. (2019). Avian malaria-mediated population decline of a widespread iconic bird species. Royal Society Open Science, 6(7), 182197. https://doi.org/10.1098/rsos.182197

Parasites have the capacity to affect animal populations by modifying host survival, and it is increasingly recognised that infectious disease can negatively impact biodiversity. Populations of the house sparrow (Passer domesticus) have declined in m... Read More about Avian malaria-mediated population decline of a widespread iconic bird species.

Physics of animal health: on the mechano-biology of hoof growth and form (2019)
Journal Article
Al-Agele, R., Paul, E., Taylor, S., Watson, C., Sturrock, C., Drakopoulos, M., …Rauch, C. (2019). Physics of animal health: on the mechano-biology of hoof growth and form. Interface, 16(155), 1-12. https://doi.org/10.1098/rsif.2019.0214

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of animal health: on the mechano-biology of hoof growth and form.

Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles (2019)
Journal Article
Mohammed, A., Woad, K. J., Mann, G. E., Craigon, J., Raine-Fenning, N., & Robinson, R. S. (2019). Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles. Fertility and Sterility, 112(3), 491-502.e3. https://doi.org/10.1016/j.fertnstert.2019.04.021

© 2019 American Society for Reproductive Medicine Objective: To evaluate the effectiveness of progestogen supplementation in improving clinical pregnancy rates in women undergoing fresh IVF cycles and to compare different routes, start times, duratio... Read More about Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles.

Global serum proteomic changes in water buffaloes infected with Fasciola gigantica (2019)
Journal Article
Zhang, F., Hu, R., Elsheikha, H. M., Sheng, Z., Zhang, W., Zheng, W., …He, J. (2019). Global serum proteomic changes in water buffaloes infected with Fasciola gigantica. Parasites and Vectors, 12(1), Article 281. https://doi.org/10.1186/s13071-019-3533-5

Background: The liver fluke Fasciola gigantica modulates several signaling pathways in infected buffaloes to facilitate its survival and establishment of persistent infection. In response to the parasite invasion, buffaloes activate innate and adapti... Read More about Global serum proteomic changes in water buffaloes infected with Fasciola gigantica.

Using lamb sales data to investigate associations between implementation of disease preventive practices and sheep flock performance (2019)
Journal Article
Lima, E., Lovatt, F., Davies, P., & Kaler, J. (2019). Using lamb sales data to investigate associations between implementation of disease preventive practices and sheep flock performance. Animal, 13(11), 2630-2638. https://doi.org/10.1017/s1751731119001058

Although the UK is the largest lamb meat producer in Europe, there are limited data available on sheep flock performance and on how sheep farmers manage their flocks. The aims of this study were to gather evidence on the types of disease control prac... Read More about Using lamb sales data to investigate associations between implementation of disease preventive practices and sheep flock performance.

Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners (2019)
Journal Article
Bowden, A., Burford, J., Brennan, M., England, G., & Freeman, S. (2019). Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners. Veterinary Evidence, 4(2), https://doi.org/10.18849/ve.v4i2.199

Objective: The aim of this study was to evaluate equine livery yard owners’ opinions of emergency conditions, and to identify factors influencing emergency decision making in the horse. Background: There is limited data on horse owners’ opinions a... Read More about Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners.

Detection and analysis of RNA methylation (2019)
Journal Article
Mongan, N. P., Emes, R. D., & Archer, N. (2019). Detection and analysis of RNA methylation. F1000Research, 8, 559. https://doi.org/10.12688/f1000research.17956.1

© 2019 Mongan NP et al. Our understanding of the expanded genetic alphabet has been growing rapidly over the last two decades, and many of these developments came more than 80 years after the original discovery of a modified guanine in tuberculosis D... Read More about Detection and analysis of RNA methylation.