Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents

Alvaradejo, Gabriela Gil; Nguyen, Hung V.-T.; Harvey, Peter; Gallagher, Nolan M.; Le, Dao; Ottaviani, M. Francesca; Jasanoff, Alan; Delaittre, Guillaume; Johnson, Jeremiah A.

doi:10.1021/acsmacrolett.9b00016

All Outputs (2)

Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma (2019)
Journal Article
Detappe, A., Reidy, M., Yu, Y., Mathieu, C., Nguyen, H. V., Coroller, T. P., …Ghoroghchian, P. P. (2019). Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma. Nanoscale, 11(43), 20485-20496. https://doi.org/10.1039/c9nr06512a

Monitoring malignant progression and disease recurrence post-therapy are central challenges to improving the outcomes of patients with multiple myeloma (MM). Whereas current detection methods that rely upon bone marrow examination allow for precise m... Read More about Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma.

Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents (2019)
Journal Article
Alvaradejo, G. G., Nguyen, H. V., Harvey, P., Gallagher, N. M., Le, D., Ottaviani, M. F., …Johnson, J. A. (2019). Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents. ACS Macro Letters, 8(4), 473-478. https://doi.org/10.1021/acsmacrolett.9b00016

Copyright © 2019 American Chemical Society. The synthesis of functional poly(2-alkyl-2-oxazoline) (PAOx) copolymers with complex nanoarchitectures using a graft-through ring-opening metathesis polymerization (ROMP) approach is described. First, well-... Read More about Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents.