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Diagnosing dysplasia in Barrett’s oesophagus still requires Seattle protocol biopsy in the era of modern video endoscopy: results from a tertiary centre Barrett’s dysplasia database. (2019)
Journal Article
Nachiappan, A., Ragunath, K., Card, T., & Kaye, P. (2019). Diagnosing dysplasia in Barrett’s oesophagus still requires Seattle protocol biopsy in the era of modern video endoscopy: results from a tertiary centre Barrett’s dysplasia database. Scandinavian Journal of Gastroenterology, 55(1), 9-13. https://doi.org/10.1080/00365521.2019.1706762

Objectives: The role of random, four-quadrant biopsy (i.e. systematic biopsy) in Barrett’s oesophagus surveillance has been questioned given its drawbacks and the emergence of high-resolution endoscopy and advanced imaging modalities. Our study aims... Read More about Diagnosing dysplasia in Barrett’s oesophagus still requires Seattle protocol biopsy in the era of modern video endoscopy: results from a tertiary centre Barrett’s dysplasia database..

Weight management programme for overweight and obese adults in Ningbo, China: a feasibility pre- and post-intervention study (2019)
Journal Article
Xu, M., Chattopadhyay, K., Li, J., Rai, N., Chen, Y., Hu, F., …Li, L. (2019). Weight management programme for overweight and obese adults in Ningbo, China: a feasibility pre- and post-intervention study. Frontiers in Public Health, 7, Article 388. https://doi.org/10.3389/fpubh.2019.00388

Objective: To investigate the feasibility of conducting a randomized controlled trial (RCT) of a weight management programme in Ningbo, China. Methods: A pre- and post-intervention study was conducted in Ningbo. The study duration was from 01 July... Read More about Weight management programme for overweight and obese adults in Ningbo, China: a feasibility pre- and post-intervention study.

Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study (2019)
Journal Article
Ahankari, A. S., Tata, L. J., & Fogarty, A. W. (2020). Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study. Maternal and Child Nutrition, 16(2), https://doi.org/10.1111/mcn.12908

Objective: We aimed to explore the association of physical parameters with haemoglobin (Hb) levels to test the hypothesis that impaired physical development is associated with anaemia. Methods: A cross-sectional survey study recruited adolescent... Read More about Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study.

Vitamin E acetate is not present in licit e?cigarette products available on the UK market (2019)
Journal Article
Nyakutsikwa, B., Britton, J., Bogdanovica, I., & Langley, T. (2020). Vitamin E acetate is not present in licit e?cigarette products available on the UK market. Addiction, 115(4), 782-783. https://doi.org/10.1111/add.14920

Aims To determine whether nicotine-containing vaping products submitted to the Medicines and Healthcare products Regulatory Agency (MHRA) under the Tobacco and Related Products Regulations 2016 contain tetrahydrocannabinol or vitamin E acetate.... Read More about Vitamin E acetate is not present in licit e?cigarette products available on the UK market.

Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK (2019)
Journal Article
Rice, P., Williams, R., Newsome, P., Aithal, G., Morling, J., Alexander, G. J., …Yeoman, A. (2020). Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK. Lancet, 395(10219), 226-239. https://doi.org/10.1016/S0140-6736%2819%2932908-3

This final report of the Lancet Commission into liver disease in the UK stresses the continuing increase in burden of liver disease from excess alcohol consumption and obesity, with high levels of hospital admissions which are worsening in deprived a... Read More about Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK.

Challenges to implementing the WHO Framework Convention on Tobacco Control guidelines on tobacco cessation treatment: a qualitative analysis (2019)
Journal Article
Shelley, D. R., Kyriakos, C. N., McNeill, A., Murray, R., Nilan, K., Sherman, S. E., & Raw, M. (2020). Challenges to implementing the WHO Framework Convention on Tobacco Control guidelines on tobacco cessation treatment: a qualitative analysis. Addiction, 115(3), 527-533. https://doi.org/10.1111/add.14863

© 2019 Society for the Study of Addiction Aim: To identify barriers to implementing the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) Article 14 guidelines on tobacco dependence treatment (TDT). Design: Cross-sectiona... Read More about Challenges to implementing the WHO Framework Convention on Tobacco Control guidelines on tobacco cessation treatment: a qualitative analysis.

Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit (2019)
Journal Article
Nartey, Y., Stewart, I., Khakwani, A., Beattie, V., Wilcock, A., Woolhouse, I., …Tata, L. J. (2020). Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit. Lung Cancer, 140, 27-34. https://doi.org/10.1016/j.lungcan.2019.11.023

© 2019 Elsevier B.V. Objectives: Healthcare systems increasingly recognise the importance of service users’ perspectives for improving care organisation and delivery. The English Cancer Patient Experience Survey (CPES) is carried out annually, howeve... Read More about Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit.

Association of the built environment with physical activity in children and adolescents in Africa: a systematic review protocol (2019)
Journal Article
Adebusoye, B., Phalkey, R., Leonardi-Bee, J., & Chattopadhyay, K. (2020). Association of the built environment with physical activity in children and adolescents in Africa: a systematic review protocol. JBI Evidence Synthesis, 18(3), 553-563. https://doi.org/10.11124/JBISRIR-D-19-00162

Objective: The objective of this systematic review is to summarize the association of the built environment with physical activity in children and adolescents in Africa. Introduction: Physical activity offers immense benefits to children and adolesc... Read More about Association of the built environment with physical activity in children and adolescents in Africa: a systematic review protocol.

Vedolizumab use is not associated with increased malignancy incidence: GEMINI LTS study results and post-marketing data (2019)
Journal Article
Card, T., Ungaro, R., Bhayat, F., Blake, A., Hantsbarger, G., & Travis, S. (2020). Vedolizumab use is not associated with increased malignancy incidence: GEMINI LTS study results and post-marketing data. Alimentary Pharmacology and Therapeutics, 51(1), 149-157. https://doi.org/10.1111/apt.15538

© 2019 John Wiley & Sons Ltd Background: Vedolizumab is a gut-selective antibody to α4β7integrin approved to treat moderate-to-severe Crohn's disease and ulcerative colitis in adults. Inflammatory bowel disease (IBD) and immunosuppressant use are a... Read More about Vedolizumab use is not associated with increased malignancy incidence: GEMINI LTS study results and post-marketing data.

Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis (2019)
Journal Article
Lansbury, L. E., Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., & Shen Lim, W. (2020). Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis. Critical Care Medicine, 48(2), e98-e106. https://doi.org/10.1097/ccm.0000000000004093

Objective: Corticosteroids may be beneficial in sepsis but uncertainty remains over their effects in severe influenza. This systematic review updates the current evidence regarding corticosteroids in the treatment of influenza and examines the effect... Read More about Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis.

Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study (2019)
Journal Article
Young, B., Cranwell, J., Fogarty, A. W., Skelly, R., Sturrock, N., Norwood, M., …Thurley, P. (2019). Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study. BMC Health Services Research, 19, https://doi.org/10.1186/s12913-019-4712-y

Background: In the context of increasing availability of computed tomography (CT) scans, judicious use of ionising radiation is a priority to minimise the risk of future health problems. Hence, education of clinicians on the risks and benefits of CT... Read More about Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study.

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis (2019)
Journal Article
Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S., Dressen, A., Paynton, M. L., …Wain, L. V. (2020). Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 201(5), 564-574. https://doi.org/10.1164/rccm.201905-1017oc

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterised by scarring of the lung that is believed to result from an atypical response to injury of the epithelium. Genome-wide association studies have reported signals of... Read More about Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care vs usual care alone following an acute coronary event (2019)
Journal Article
Tillin, T., Tuson, C., Sowa, B., Chattopadhyay, K., Sattar, N., Welsh, P., …Chaturvedi, N. (2019). Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care vs usual care alone following an acute coronary event. BMJ Open, 9(11), Article e030119

Objective: To determine effects of yoga practice on subclinical cardiovascular measures, risk factors and neuro-endocrine pathways in patients undergoing cardiac rehabilitation following acute coronary events. Design: 3-month, two arm (yoga+usual... Read More about Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care vs usual care alone following an acute coronary event.

Diagnosis of Barrett’s esophagus and Esophageal Varices using a Magnetically Assisted Capsule Endoscopy system (2019)
Journal Article
Beg, S., Card, T., Warburton, S., Rahman, I., Wilkes, E., White, J., & Ragunath, K. (2020). Diagnosis of Barrett’s esophagus and Esophageal Varices using a Magnetically Assisted Capsule Endoscopy system. Gastrointestinal Endoscopy, 91(4), 773-781.e1. https://doi.org/10.1016/j.gie.2019.10.031

Background and Aims Magnetically assisted capsule endoscopy (MACE) potentially offers a comfortable, patient friendly, and community-based alternative to gastroscopy (EGD). This pilot study aims to explore whether this approach can be used to accura... Read More about Diagnosis of Barrett’s esophagus and Esophageal Varices using a Magnetically Assisted Capsule Endoscopy system.

Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis (2019)
Journal Article
Webb, K., Fogarty, A., Barrett, D. A., Nash, E. F., Whitehouse, J. L., Smyth, A. R., …Cámara, M. (2019). Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis. Journal of Medical Microbiology, 68(12), 1823-1828. https://doi.org/10.1099/jmm.0.001099

Introduction : Pseudomonas aeruginosa is an important respiratory pathogen in cystic fibrosis (CF), which is associated with an accelerated decline in lung function, frequent pulmonary exacerbations and increased mortality. P. aeruginosa produces in... Read More about Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.

The psychosis treatment gap and its consequences in rural Ethiopia (2019)
Journal Article
Fekadu, A., Medhin, G., Lund, C., DeSilva, M., Selamu, M., Alem, A., …Hanlon, C. (2019). The psychosis treatment gap and its consequences in rural Ethiopia. BMC Psychiatry, 19, Article 325. https://doi.org/10.1186/s12888-019-2281-6

Background The “treatment gap” (TG) for mental disorders, widely advocated by the WHO in low-and middle-income countries, is an important indicator of the extent to which a health system fails to meet the care needs of people with mental disorder at... Read More about The psychosis treatment gap and its consequences in rural Ethiopia.

A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic (2019)
Journal Article
Venkatesan, S., Nguyen-Van-Tam, J., & Siebers, P. (2019). A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic. PLoS ONE, 14(10), https://doi.org/10.1371/journal.pone.0223946

© 2019 Venkatesan et al. The importance of accounting for social and behavioural processes when studying public health emergencies has been well-recognised. For infectious disease outbreaks in particular, several methods of incorporating individual b... Read More about A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic.

Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study (2019)
Journal Article
Lewis, S., Young, B., Thurley, P., Shaw, D., Cranwell, J., Skelly, R., …Fogarty, A. W. (2019). Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study. Future Healthcare Journal, 6(3), 204-208. https://doi.org/10.7861/fhj.2019-0001

Background: Behavioural insights or ‘nudge’ theory suggests that non-directional interventions may be used to modify human behaviour. We have tested the hypothesis that the provision of the cost of common blood tests with their results may modify sub... Read More about Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study.

Rojiroti microfinance and child nutrition: a cluster randomised trial (2019)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A., Allen, S., …Smyth, A. R. (2020). Rojiroti microfinance and child nutrition: a cluster randomised trial. Archives of Disease in Childhood, 105(3), 229-235. https://doi.org/10.1136/archdischild-2018-316471

Objective To determine whether Rojiroti microfinance, for poor Indian women, improves child nutrition. Design Cluster randomised trial. Setting Tolas (village communities) in Bihar State. Participants Women and children under 5 years. Int... Read More about Rojiroti microfinance and child nutrition: a cluster randomised trial.