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Osteocalcin does not influence acute or chronic inflammation in human vascular cells (2019)
Journal Article
Millar, S. A., Zala, I., Anderson, S. I., & O'Sullivan, S. E. (2020). Osteocalcin does not influence acute or chronic inflammation in human vascular cells. Journal of Cellular Physiology, 235(4), 3414-3424. https://doi.org/10.1002/jcp.29231

Some human observational studies have suggested an anti-inflammatory role of osteocalcin (OCN). An inflammatory protocol using IFN-γ and TNF-α (10 ng/mL) was employed to examine the acute (24 hr) and chronic (144 hr) effects of uncarboxylated OCN (uc... Read More about Osteocalcin does not influence acute or chronic inflammation in human vascular cells.

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae (2019)
Journal Article
Overbey, E. G., Paul, A. M., da Silveira, W. A., Tahimic, C. G., Reinsch, S. S., Szewczyk, N., …Mao, X. W. (2019). Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae. International Journal of Molecular Sciences, 20(17), Article 4094. https://doi.org/10.3390/ijms20174094

Spaceflight poses many challenges for humans. Ground-based analogs typically focus on single parameters of spaceflight and their associated acute effects. This study assesses the long-term transcriptional effects following single and combination spac... Read More about Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae.

The treatment of hypertension in people with dementia: a multi-centre prospective observational cohort study (2019)
Journal Article
Welsh, T., Gladman, J., & Gordon, A. (2019). The treatment of hypertension in people with dementia: a multi-centre prospective observational cohort study. Journal of the American Medical Directors Association, 20(9), 1111-1115. https://doi.org/10.1016/j.jamda.2019.03.036

Objectives To describe the treatment of hypertension in people with dementia and collate evidence on adverse health events whilst on treatment. Design A multicenter prospective observational cohort study. Setting and participants People with... Read More about The treatment of hypertension in people with dementia: a multi-centre prospective observational cohort study.