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Pair-based likelihood approximations for stochastic epidemic models (2019)
Journal Article
Stockdale, J. E., Kypraios, T., & O'Neill, P. D. (2021). Pair-based likelihood approximations for stochastic epidemic models. Biostatistics, 22(3), 575-597. https://doi.org/10.1093/biostatistics/kxz053

Fitting stochastic epidemic models to data is a non-standard problem because data on the infection processes defined in such models are rarely observed directly. This in turn means that the likelihood of the observed data is intractable in the sense... Read More about Pair-based likelihood approximations for stochastic epidemic models.

A statistical view on calcium oscillations (2019)
Journal Article
Powell, J., Falcke, M., Skupin, A., Bellamy, T., Kypraios, T., & Thul, R. (2019). A statistical view on calcium oscillations. Advances in Experimental Medicine and Biology, 1131, 799-826. https://doi.org/10.1007/978-3-030-12457-1_32

Transient rises and falls of the intracellular calcium concentration have been observed in numerous cell types and under a plethora of conditions. There is now a growing body of evidence that these whole-cell calcium oscillations are stochastic, whic... Read More about A statistical view on calcium oscillations.

An Integrated Pipeline for Combining in vitro Data and Mathematical Models Using a Bayesian Parameter Inference Approach to Characterize Spatio-temporal Chemokine Gradient Formation (2019)
Journal Article
Kalogiros, D. I., Russell, M., Bonneuil, W., Frattolin, J., Watson, D., Moore Jr, J. E., …Brook, B. S. (2019). An Integrated Pipeline for Combining in vitro Data and Mathematical Models Using a Bayesian Parameter Inference Approach to Characterize Spatio-temporal Chemokine Gradient Formation. Frontiers in Immunology, 10, Article 1986. https://doi.org/10.3389/fimmu.2019.01986

All protective and pathogenic immune and inflammatory responses rely heavily on leukocyte migration and localization. Chemokines are secreted chemoattractants that orchestrate the positioning and migration of leukocytes through concentration gradient... Read More about An Integrated Pipeline for Combining in vitro Data and Mathematical Models Using a Bayesian Parameter Inference Approach to Characterize Spatio-temporal Chemokine Gradient Formation.

A comparative study of estimation methods in quantum tomography (2019)
Journal Article
Acharya, A., Kypraios, T., & Guta, M. (2019). A comparative study of estimation methods in quantum tomography. Journal of Physics A: Mathematical and Theoretical, 52(23), 1-36. https://doi.org/10.1088/1751-8121/ab1958

As quantum tomography is becoming a key component of the quantum engineering toolbox, there is a need for a deeper understanding of the multitude of estimation methods available. Here we investigate and compare several such methods: maximum likelihoo... Read More about A comparative study of estimation methods in quantum tomography.

Standardised profiling for tinnitus research: the European School for Interdisciplinary Tinnitus Research Screening Questionnaire (ESIT-SQ) (2019)
Journal Article
Genitsaridi, E., Partyka, M., Gallus, S., Lopez-Escamez, J. A., Schecklmann, M., Mielczarek, M., …Hall, D. A. (2019). Standardised profiling for tinnitus research: the European School for Interdisciplinary Tinnitus Research Screening Questionnaire (ESIT-SQ). Hearing Research, 377, 353-359. https://doi.org/10.1016/j.heares.2019.02.017

Background The heterogeneity of tinnitus is substantial. Its numerous pathophysiological mechanisms and clinical manifestations have hampered fundamental and treatment research significantly. A decade ago, the Tinnitus Research Initiative introduced... Read More about Standardised profiling for tinnitus research: the European School for Interdisciplinary Tinnitus Research Screening Questionnaire (ESIT-SQ).