HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1
(2019)
Journal Article
Ghosh, T. K., Aparicio-Sánchez, J. J., Buxton, S., & Brook, J. D. (2019). HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1. Scientific Reports, 9, Article 17992. https://doi.org/10.1038/s41598-019-54312-w
TBX5 is a T-box family transcription factor that regulates heart and forelimb development in vertebrates and functional deficiencies in this protein result in Holt-Oram syndrome. Recently, we have shown that acetylation of TBX5 potentiates its activi... Read More about HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1.