Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum

Patient, Jamie D.; Hajiali, Hadi; Harris, Kate; Abrahamsson, Bertil; Tannergreen, Christopher; White, Lisa J.; Ghaemmaghami, Amir M.; Williams, Philip M.; Roberts, Clive J.; Rose, Felicity R.A.J.

doi:10.3389/fphar.2019.00456

All Outputs (2)

Evolutionary Drivers of Protein Shape (2019)
Journal Article
Shannon, G., Marples, C. R., Toofanny, R. D., & Williams, P. M. (2019). Evolutionary Drivers of Protein Shape. Scientific Reports, 9(1), https://doi.org/10.1038/s41598-019-47337-8

Diffusional motion within the crowded environment of the cell is known to be crucial to cellular function as it drives the interactions of proteins. However, the relationships between protein diffusion, shape and interaction, and the evolutionary sel... Read More about Evolutionary Drivers of Protein Shape.

Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum (2019)
Journal Article
Patient, J. D., Hajiali, H., Harris, K., Abrahamsson, B., Tannergreen, C., White, L. J., …Rose, F. R. (2019). Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum. Frontiers in Pharmacology, 10, Article 456. https://doi.org/10.3389/fphar.2019.00456

Advances in drug research not only depend on high throughput screening to evaluate large numbers of lead compounds but also on the development of in vitro models which can simulate human tissues in terms of drug permeability and functions. Potential... Read More about Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum.