All Outputs (5)

Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation (2019)
Journal Article
Walker, C., Siu-Ting, K., Taylor, A., O'Connell, M. J., & Bennett, T. (2019). Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation. BMC Biology, 17, 1-19. https://doi.org/10.1186/s12915-019-0689-6

Background Strigolactones (SLs) are an important class of carotenoid-derived signalling molecule in plants, which function both as exogenous signals in the rhizosphere and as endogenous plant hormones. In flowering plants, SLs are synthesized by a c... Read More about Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation.

Gene Fusions derived by transcriptional readthrough are Driven by Segmental Duplication in Human (2019)
Journal Article
Mccartney, A., Hyland, E., Cormican, P., Moran, R., Webb, A., Lee, K., …O'Connell, M. (2019). Gene Fusions derived by transcriptional readthrough are Driven by Segmental Duplication in Human. Genome Biology and Evolution, 11(9), 2678-2690. https://doi.org/10.1093/gbe/evz163

Gene fusion occurs when two or more individual genes with independent open reading frames becoming juxtaposed under the same open reading frame creating a new fused gene. A small number of gene fusions described in detail have been associated with no... Read More about Gene Fusions derived by transcriptional readthrough are Driven by Segmental Duplication in Human.

Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an assembly for the humpback whale (Megaptera novaeangliae) (2019)
Journal Article
Tollis, M., Robbins, J., Webb, A. E., Kuderna, L. F., Caulin, A. F., Garcia, J. D., …Maley, C. C. (2019). Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an assembly for the humpback whale (Megaptera novaeangliae). Molecular Biology and Evolution, 36(8), 1746-1763. https://doi.org/10.1093/molbev/msz099

Cetaceans are a clade of highly specialized aquatic mammals that include the largest animals that have ever lived. The largest whales can have ~1000X more cells than a human, with long lifespans, leaving them theoretically susceptible to cancer. Howe... Read More about Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an assembly for the humpback whale (Megaptera novaeangliae).

Paternally expressed imprinted genes under positive Darwinian selection in Arabidopsis thaliana (2019)
Journal Article
Tuteja, R., McKeown, P. C., Ryan, P., Morgan, C. C., Donoghue, M. T., Downing, T., …Spillane, C. (2019). Paternally expressed imprinted genes under positive Darwinian selection in Arabidopsis thaliana. Molecular Biology and Evolution, 36(6), 1239–1253. https://doi.org/10.1093/molbev/msz063

Genomic imprinting is an epigenetic phenomenon where autosomal genes display uniparental expression depending on whether they are maternally or paternally inherited. Genomic imprinting can arise from parental conflicts over resource allocation to the... Read More about Paternally expressed imprinted genes under positive Darwinian selection in Arabidopsis thaliana.

Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics (2019)
Journal Article
Siu-Ting, K., Torres-Sánchez, M., San Mauro, D., Wilcockson, D., Wilkinson, M., Pisani, D., …Creevey, C. J. (2019). Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics. Molecular Biology and Evolution, 36(6), 1344-1356. https://doi.org/10.1093/molbev/msz067

Increasingly, large phylogenomic datasets include transcriptomic data from non-model organisms. This has allowed controversial and unexplored evolutionary relationships in the tree of life to be addressed but also increases the risk of inadvertent in... Read More about Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics.