Skip to main content

Research Repository

Advanced Search

All Outputs (3)

Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease (2019)
Journal Article
Agostini, A., Yuchun, D., Li, B., Kendall, D. A., & Pardon, M. (2020). Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Brain, Behavior, and Immunity, 83, 87-111. https://doi.org/10.1016/j.bbi.2019.09.019

Systemic inflammation enhances the risk and progression of Alzheimer's disease (AD). Lipopolysaccharide (LPS), a potent pro-inflammatory endotoxin produced by the gut, is found in excess levels in AD where it associates with neurological hallmarks of... Read More about Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease.

Myoinositol CEST signal in animals with increased Iba-1 levels in response to an inflammatory challenge—Preliminary findings (2019)
Journal Article
Yanez Lopez, M., Pardon, M., Baiker, K., Prior, M., Yuchun, D., Agostini, A., …Faas, H. M. (2019). Myoinositol CEST signal in animals with increased Iba-1 levels in response to an inflammatory challenge—Preliminary findings. PLoS ONE, 14(2), Article e0212002. https://doi.org/10.1371/journal.pone.0212002

Neuroinflammation plays an important role in the pathogenesis of a range of brain disorders. Non-invasive imaging of neuroinflammation is critical to help improve our understanding of the underlying disease mechanisms, monitor therapies and guide dru... Read More about Myoinositol CEST signal in animals with increased Iba-1 levels in response to an inflammatory challenge—Preliminary findings.

Accurate Monte Carlo simulation of frequency-domain optical coherence tomography (2019)
Journal Article
Wang, Y., & Bai, L. (2019). Accurate Monte Carlo simulation of frequency-domain optical coherence tomography. International Journal for Numerical Methods in Biomedical Engineering, 35(4), Article e3177. https://doi.org/10.1002/cnm.3177

Optical coherence Tomography (OCT) relies on optical interferometry to provide non‐invasive imaging of living tissues. In addition to its 3D imaging capacity for medical diagnosis, its potential use for recovering optical parameters of biological tis... Read More about Accurate Monte Carlo simulation of frequency-domain optical coherence tomography.