Localized induction of gene expression in embryonic stem cell aggregates using holographic optical tweezers to create biochemical gradients
(2019)
Journal Article
Kirkham, G. R., Ware, J., Upton, T., Allen, S., Shakesheff, K. M., & Buttery, L. D. (2020). Localized induction of gene expression in embryonic stem cell aggregates using holographic optical tweezers to create biochemical gradients. Regenerative Engineering and Translational Medicine, 6(3), 251–261. https://doi.org/10.1007/s40883-019-00114-5
Three dimensional (3D) cell models that mimic the structure and function of native tissues are enabling more detailed study of physiological and pathological mechanisms in vitro. We have previously demonstrated the ability to build and manipulate 3D... Read More about Localized induction of gene expression in embryonic stem cell aggregates using holographic optical tweezers to create biochemical gradients.