All Outputs (4)

Microfluidic-based Growth and Imaging of Bacterial Biofilms (2019)
Journal Article
Brown, J., Blunk, B., Williams, P., & Hardie, K. (2019). Microfluidic-based Growth and Imaging of Bacterial Biofilms. Bio-protocol, 9(24), https://doi.org/10.21769/BioProtoc.3460

Biofilms are a ubiquitous form of growth for bacteria on surfaces in most environments, natural or manmade. Here we present a protocol using the Bioflux microfluidic system to investigate the organized structure and development of these multicellular... Read More about Microfluidic-based Growth and Imaging of Bacterial Biofilms.

Improving children’s and their visitors’ hand hygiene compliance (2019)
Journal Article
Lary, D., Calvert, A., Nerlich, B., Segal, J., Vaughan, N., Randle, J., & Hardie, K. (2020). Improving children’s and their visitors’ hand hygiene compliance. Journal of Infection Prevention, 21(2), 60-67. https://doi.org/10.1177/1757177419892065

Background: Numerous interventions have tried to improve healthcare workers' hand hygiene compliance, however little attention has been paid to children's and their visitors’ compliance. Aim: To increase children’s and visitors’ compliance using in... Read More about Improving children’s and their visitors’ hand hygiene compliance.

Dual Bioresponsive Antibiotic and Quorum Sensing Inhibitor Combination Nanoparticles for Treatment of Pseudomonas aeruginosa Biofilms In Vitro and Ex Vivo (2019)
Journal Article
Singh, N., Romero, M., Travanut, A., Monteiro, P., Jordana-Lluch, E., Hardie, K. R., …Alexander, C. (2019). Dual Bioresponsive Antibiotic and Quorum Sensing Inhibitor Combination Nanoparticles for Treatment of Pseudomonas aeruginosa Biofilms In Vitro and Ex Vivo. Biomaterials Science, 10(7), 4099-4111. https://doi.org/10.1039/C9BM00773C

Many debilitating infections result from persistent microbial biofilms that do not respond to conventional antibiotic regimens. A potential method to treat such chronic infections is to combine agents which interfere with bacterial biofilm developmen... Read More about Dual Bioresponsive Antibiotic and Quorum Sensing Inhibitor Combination Nanoparticles for Treatment of Pseudomonas aeruginosa Biofilms In Vitro and Ex Vivo.

Where bacterial metabolism and virulence intersect (2019)
Journal Article
Hardie, K. (2019). Where bacterial metabolism and virulence intersect. Microbiology Today, 46(2), 58-61

‘We are what we eat’, and so are the bacteria that live on us. If bacteria do not have the building blocks or metabolic pathways and capacity to create their healthy cell, they will be disadvantaged when it comes to establishing an infection.