All Outputs (3)

Mathematical and Computational Modelling in Critical Illness (2019)
Journal Article
Laviola, M., Bates, D. G., & Hardman, J. G. (2019). Mathematical and Computational Modelling in Critical Illness. European Respiratory & Pulmonary Diseases, 5(1),

Mathematical and computational modelling are assuming a prominent role in investigating the complex pathophysiological states and therapeutic strategies in critical illness. This editorial briefly illustrates the models of the respiratory and cardiov... Read More about Mathematical and Computational Modelling in Critical Illness.

High oxygen fraction during airway opening is key to effective airway rescue in obese subjects (2019)
Conference Proceeding
Laviola, M., Christian, N., Alahmadi, H., Das, A., Bates, D. G., & Hardman, J. G. (2019). High oxygen fraction during airway opening is key to effective airway rescue in obese subjects. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2357-2360). https://doi.org/10.1109/EMBC.2019.8857109

Apnea is common after induction of anesthesia and may produce dangerous hypoxemia, particularly in obese subjects. Optimal management of airway emergencies in obese, apneic subjects is complex and controversial, and clinical studies of rescue strateg... Read More about High oxygen fraction during airway opening is key to effective airway rescue in obese subjects.

Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial (2019)
Journal Article
Hewson, D. W., Worcester, F., Sprinks, J., Smith, M. D., Buchanan, H., Breedon, P., …Bedforth, N. M. (2019). Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial. Trials, 20(1), Article 129. https://doi.org/10.1186/s13063-019-3228-4

Background The clinical efficacy of effect-site targeted patient-maintained propofol sedation (PMPS) compared to anaesthetist-controlled propofol sedation (ACPS) for patients undergoing awake joint replacement surgery is currently unknown. There is... Read More about Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial.