All Outputs (7)

Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study (2019)
Journal Article
Mamza, J., Anyanwagu, U., Alkharaiji, M., & Idris, I. (2020). Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study. Journal of Drug Assessment, 9(1), 8-12. https://doi.org/10.1080/21556660.2019.1704415

Background There is limited data on the real world evidence of Humalog 200 units/ml KwikPen (U-200) insulin. We assessed the use of U-200 insulin in UK routine clinical practice to provide information on clinical characteristics, treatment satisfacti... Read More about Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study.

Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men (2019)
Journal Article
Gharahdaghi, N., Rudrappa, S., Brook, M. S., Idris, I., Crossland, H., Hamrock, C., …Atherton, P. J. (2019). Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men. Journal of Cachexia, Sarcopenia and Muscle, 10(6), 1276-1294. https://doi.org/10.1002/jcsm.12472

Background: The andropause is associated with declines in serum testosterone (T), loss of muscle mass (sarcopenia) and frailty. Two major interventions purported to offset sarcopenia are anabolic steroid therapies and resistance exercise training (RE... Read More about Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men.

Effect of Bariatric Surgery on Cardiovascular Events and Metabolic Outcomes in Obese Patients with Insulin-Treated Type 2 Diabetes: a Retrospective Cohort Study (2019)
Journal Article
Alkharaiji, M., Anyanwagu, U., Donnelly, R., & Idris, I. (2019). Effect of Bariatric Surgery on Cardiovascular Events and Metabolic Outcomes in Obese Patients with Insulin-Treated Type 2 Diabetes: a Retrospective Cohort Study. Obesity Surgery, 29(10), 3154-3164. https://doi.org/10.1007/s11695-019-03809-4

© 2019, Springer Science+Business Media, LLC, part of Springer Nature. Aims: To compare non-fatal cardiovascular (CV) events and metabolic outcomes, among obese patients with insulin-treated type 2 diabetes who underwent bariatric surgery compared wi... Read More about Effect of Bariatric Surgery on Cardiovascular Events and Metabolic Outcomes in Obese Patients with Insulin-Treated Type 2 Diabetes: a Retrospective Cohort Study.

The effect of oral essential amino acids on incretin hormone production in youth and ageing (2019)
Journal Article
Abdulla, H., Bass, J., Stokes, T., Gorissen, S., McGlory, C., Phillips, B., …Atherton, P. (2019). The effect of oral essential amino acids on incretin hormone production in youth and ageing. Endocrinology, Diabetes and Metabolism, 2(4), Article e00085. https://doi.org/10.1002/edm2.85

Background The effect of substantive doses of essential amino acids (EAA) on incretin and insulin production, and the impact of age upon this effect, is ill‐defined. Methods A 15‐g oral EAA drink was administered to young (N = 8; 26 ± 4.4 years)... Read More about The effect of oral essential amino acids on incretin hormone production in youth and ageing.

Efficacy and Safety of Pioglitazone Monotherapy in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomised Controlled Trials (2019)
Journal Article
Alam, F., Islam, M. A., Mohamed, M., Ahmad, I., Kamal, M. A., Donnelly, R., …Gan, S. H. (2019). Efficacy and Safety of Pioglitazone Monotherapy in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Scientific Reports, 9, Article 5389. https://doi.org/10.1038/s41598-019-41854-2

Pioglitazone, the only thiazolidinedione drug in clinical practice is under scrutiny due to reported adverse effects, it’s unique insulin sensitising action provides rationale to remain as a therapeutic option for managing type 2 diabetes mellitus (T... Read More about Efficacy and Safety of Pioglitazone Monotherapy in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Albuminuria regression and all-cause mortality among insulin-treated patients with Type 2 diabetes: analysis of a large UK Primary Care cohort (2019)
Journal Article
Anyanwagu, U., Donnelly, R., & Idris, I. (2019). Albuminuria regression and all-cause mortality among insulin-treated patients with Type 2 diabetes: analysis of a large UK Primary Care cohort. American Journal of Nephrology, 49(2), 146-155. https://doi.org/10.1159/000496276

Background: Overt albuminuria (urinary albumin-creatinine ratio (ACR) >300mg/g) is an established risk factor for progression of nephropathy and total mortality. However, whether, a reduction in ACR translates into a reduction in mortality and/or car... Read More about Albuminuria regression and all-cause mortality among insulin-treated patients with Type 2 diabetes: analysis of a large UK Primary Care cohort.

Relationship between HbA1c and all-cause mortality in older patients with insulin treated Type 2 diabetes: results of a large UK cohort study (2019)
Journal Article
Askandar, I. (2019). Relationship between HbA1c and all-cause mortality in older patients with insulin treated Type 2 diabetes: results of a large UK cohort study. Age and Ageing, 48(2), 235-240