All Outputs (5)

Data showing regional differences in rat brain monoaminergic function (2019)
Journal Article
Nelson, A. .., & Cassaday, H. (2019). Data showing regional differences in rat brain monoaminergic function. Data in Brief, 27, https://doi.org/10.1016/j.dib.2019.104814

Chemical neurotransmitters (such as dopamine) modulate cognitive function via ascending projections to various cortical and sub-cortical brain regions. This report describes and links to a relatively large dataset (up to N=112) compiled from control... Read More about Data showing regional differences in rat brain monoaminergic function.

Intraperitoneal 8-OH-DPAT reduces competition from contextual but not discrete conditioning cues (2019)
Journal Article
Cassaday, H., & Thur, K. (2019). Intraperitoneal 8-OH-DPAT reduces competition from contextual but not discrete conditioning cues. Pharmacology Biochemistry and Behavior, 187, 1-6. https://doi.org/10.1016/j.pbb.2019.172797

The effects of the serotonergic (5-hydroxytryptamine, 5-HT) agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT; 0.2 and 0.4 mg/kg i.p.) were examined in trace conditioning (Experiment 1) and overshadowing (Experiment 2) procedures. Both experi... Read More about Intraperitoneal 8-OH-DPAT reduces competition from contextual but not discrete conditioning cues.

EMD386088 (5 mg/kg) has no effect on latent inhibition shown to both light and noise stimuli (2019)
Journal Article
Cassaday, H. J., & Thur, K. E. (2020). EMD386088 (5 mg/kg) has no effect on latent inhibition shown to both light and noise stimuli. Journal of Psychopharmacology, 34(1), 145-147. https://doi.org/10.1177/0269881119882855

Activation of 5-HT6 receptors stimulates attentional switching and 5-HT6 receptor antagonists are putative drugs for psychosis. Latent inhibition (LI) provides a pre-clinical model of attentional switching and ‘antipsychotic-like’ action and is known... Read More about EMD386088 (5 mg/kg) has no effect on latent inhibition shown to both light and noise stimuli.

Age-related differences in appetitive trace conditioning and novel object recognition procedures (2019)
Journal Article
Marshall, H., Pezze, M., Fone, K., & Cassaday, H. (2019). Age-related differences in appetitive trace conditioning and novel object recognition procedures. Neurobiology of Learning and Memory, 164, https://doi.org/10.1016/j.nlm.2019.107041

Appetitive trace conditioning (TC) was examined over 6 months in younger-adult (2-8 months) and middle-aged (12-18 months) male Wistar RccHan rats to test for early age-related impairment in working memory. Novel object recognition (NOR) was included... Read More about Age-related differences in appetitive trace conditioning and novel object recognition procedures.

Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning (2019)
Journal Article
Stubbendorff, C., Hale, E., Cassaday, H. J., Bast, T., & Stevenson, C. W. (2019). Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning. Psychopharmacology, 236(6), 1771-1782. https://doi.org/10.1007/s00213-018-5162-7

Rationale Dopamine D1 receptor (D1R) signalling is involved in contextual fear conditioning. The D1R antagonist SCH23390 impairs the acquisition of contextual fear when administered systemically or infused locally into the dorsal hippocampus or ba... Read More about Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning.