All Outputs (3)

The moonlighting peroxiredoxin-glutaredoxin in Neisseria meningitidis binds plasminogen via a C-terminal lysine residue and contributes to survival in a whole blood model (2019)
Journal Article
Aljannat, M. A., Oldfield, N. J., Albasri, H. M., Dorrington, L. K., Ohri, R. L., Wooldridge, K. G., & Turner, D. P. (2020). The moonlighting peroxiredoxin-glutaredoxin in Neisseria meningitidis binds plasminogen via a C-terminal lysine residue and contributes to survival in a whole blood model. Microbial Pathogenesis, 139, Article 103890. https://doi.org/10.1016/j.micpath.2019.103890

© 2019 Elsevier Ltd Neisseria meningitidis is a human-restricted bacterium that can invade the bloodstream and cross the blood-brain barrier resulting in life-threatening sepsis and meningitis. Meningococci express a cytoplasmic peroxiredoxin-glutare... Read More about The moonlighting peroxiredoxin-glutaredoxin in Neisseria meningitidis binds plasminogen via a C-terminal lysine residue and contributes to survival in a whole blood model.

Potentiation of phase variation in multiple outer membrane proteins during spread of the hyperinvasive Neisseria meningitidis serogroup W ST-11 lineage (2019)
Journal Article
Green, L. R., Dave, N., Adewoye, A. B., Lucidarme, J., Clark, S. A., Oldfield, N. J., …Bayliss, C. D. (2019). Potentiation of phase variation in multiple outer membrane proteins during spread of the hyperinvasive Neisseria meningitidis serogroup W ST-11 lineage. Journal of Infectious Diseases, 220(7), 1109–1117. https://doi.org/10.1093/infdis/jiz275

BACKGROUND: Since 2009, increases in invasive meningococcal disease have occurred in the United Kingdom due to a sub-lineage of the Neisseria meningitidis serogroup W ST-11 clonal complex (the 'original-UK' strain). In 2013, a descendent sub-strain... Read More about Potentiation of phase variation in multiple outer membrane proteins during spread of the hyperinvasive Neisseria meningitidis serogroup W ST-11 lineage.

Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis (2019)
Journal Article
Peterson, M. E., Li, Y., Shanks, H., Mile, R., Nair, H., Kyaw, M. H., & Meningococcal Carriage Group. (2019). Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis. BMJ Open, 9(4), Article e024343. https://doi.org/10.1136/bmjopen-2018-024343

Objective Neisseria meningitidis carriage prevalence has known variation across the lifespan, but it is unclear whether carriage varies among meningococcal capsular groups. Therefore, we aimed to characterise group-specific meningococcal carriage by... Read More about Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis.