All Outputs (4585)

Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink (2018)
Journal Article
Abhishek, A., Nakafero, G., Kuo, C., Mallen, C., Zhang, W., Grainge, M. J., & Doherty, M. (2018). Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink. Rheumatology, 57(6), 977–981. https://doi.org/10.1093/rheumatology/key013

Objectives: To examine temporal trends in all-cause and cause-specific mortality in RA. Methods: Data from the Clinical Practice Research Datalink (CPRD) were used. Incident RA cases and four age, sex and general practice matched controls were id... Read More about Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink.

A novel spatiotemporal home heating controller design: system emulation and field testing (2018)
Journal Article
Kruusimagi, M., Sharples, S., & Robinson, D. (2018). A novel spatiotemporal home heating controller design: system emulation and field testing. Building and Environment, 135, https://doi.org/10.1016/j.buildenv.2018.02.027

We have developed a spatiotemporal heating control algorithm for use in homes. This system utilises a combination of relatively low-tech hardware interfaced with electric heating systems and a smartphone interface to this hardware, and a central serv... Read More about A novel spatiotemporal home heating controller design: system emulation and field testing.

Facilitating ecosystem assembly: plant-soil interactions as a restoration tool (2018)
Journal Article
van der Bij, A., Weijters, M., Robbink, R., Harris, J., Pawlett, M., Ritz, K., …van Diggelen, R. (2018). Facilitating ecosystem assembly: plant-soil interactions as a restoration tool. Biological Conservation, 220, https://doi.org/10.1016/j.biocon.2018.02.010

Although plant-soil interactions are increasingly recognized as an important factor in ecosystem restoration, their effects on community assembly during de novo ecosystem establishment are largely unknown. In a heathland restoration trial after topso... Read More about Facilitating ecosystem assembly: plant-soil interactions as a restoration tool.

Improved NOE fitting for flexible molecules based on molecular mechanics data – a case study with S-adenosylmethionine (2018)
Journal Article
Bame, J., Hoeck, C., Carrington, M. J., Butts, C. P., Jäger, C. M., & Croft, A. K. (2018). Improved NOE fitting for flexible molecules based on molecular mechanics data – a case study with S-adenosylmethionine. Physical Chemistry Chemical Physics, 11(20), https://doi.org/10.1039/C7CP07265A

The use of molecular dynamics (MD) calculations to derive relative populations of conformers is highly sensitive to both timescale and parameterisation of the MD. Where these calculations are coupled with NOE data to determine the dynamics of a molec... Read More about Improved NOE fitting for flexible molecules based on molecular mechanics data – a case study with S-adenosylmethionine.

Switching the uniaxial magnetic anisotropy by ion irradiation induced compensation (2018)
Journal Article
Yuan, Y., Amarouche, T., Xu, C., Rushforth, A., Böttger, R., Edmonds, K., …Zhou, S. (2018). Switching the uniaxial magnetic anisotropy by ion irradiation induced compensation. Journal of Physics D: Applied Physics, 51(14), https://doi.org/10.1088/1361-6463/aab1db

© 2018 IOP Publishing Ltd. In the present work, the uniaxial magnetic anisotropy of GaMnAsP is modified by helium ion irradiation. According to the micro-magnetic parameters, e.g. resonance fields and anisotropy constants deduced from ferromagnetic r... Read More about Switching the uniaxial magnetic anisotropy by ion irradiation induced compensation.

Health service factors that affect adherence to tuberculosis treatment in Ghana (2018)
Journal Article
Salifu, Y., Eliason, C., & Mensah, G. (2018). Health service factors that affect adherence to tuberculosis treatment in Ghana. Primary Health Care, 28(2), 27-33. https://doi.org/10.7748/phc.2018.e1312

Most of the global cases of tuberculosis (TB) are found in Asia and Africa. This is largely due to deficient educational information, myths, beliefs and suboptimal service delivery as a result of inadequate infrastructure. Even though proper treatmen... Read More about Health service factors that affect adherence to tuberculosis treatment in Ghana.

Multiparameter estimation in networked quantum sensors (2018)
Journal Article
Proctor, T. J., Knott, P. A., & Dunningham, J. A. (2018). Multiparameter estimation in networked quantum sensors. Physical Review Letters, 120(8), https://doi.org/10.1103/PhysRevLett.120.080501

We introduce a general model for a network of quantum sensors, and we use this model to consider the following question: When can entanglement between the sensors, and/or global measurements, enhance the precision with which the network can measure a... Read More about Multiparameter estimation in networked quantum sensors.

A systematic review and meta-synthesis of the qualitative research into mandatory personal psychotherapy during training (2018)
Journal Article
Murphy, D., Irfan, N., Barnett, H., Castledine, E., & Enescu, L. (in press). A systematic review and meta-synthesis of the qualitative research into mandatory personal psychotherapy during training. Counselling and Psychotherapy Research, 18(2), https://doi.org/10.1002/capr.12162

Background: This study addresses the thorny issue of mandatory personal psychotherapy within counselling and psychotherapy training. It is expensive, emotionally demanding and time-consuming. Nevertheless, proponents argue that it is essential in pro... Read More about A systematic review and meta-synthesis of the qualitative research into mandatory personal psychotherapy during training.

Impact of the Macmillan specialist Care at Home service: a mixed methods evaluation across six sites (2018)
Journal Article
Johnston, B., Patterson, A., Bird, L., Wilson, E., Almack, K., Mathews, G., & Seymour, J. (2018). Impact of the Macmillan specialist Care at Home service: a mixed methods evaluation across six sites. BMC Palliative Care, 17(1), https://doi.org/10.1186/s12904-018-0281-9

Background: The Midhurst Macmillan Specialist Palliative Care at Home Service was founded in 2006 to improve community-based palliative care provision. Principal components include; early referral; home-based clinical interventions; close partnershi... Read More about Impact of the Macmillan specialist Care at Home service: a mixed methods evaluation across six sites.

Random duodenal biopsy to exclude coeliac disease as a cause of anaemia is not cost‑efective and should be replaced with universally performed pre‑endoscopy serology in patients on a suspected cancer pathway (2018)
Journal Article
Herrod, P., & Lund, J. N. (in press). Random duodenal biopsy to exclude coeliac disease as a cause of anaemia is not cost‑efective and should be replaced with universally performed pre‑endoscopy serology in patients on a suspected cancer pathway. Techniques in Coloproctology, 22(2), https://doi.org/10.1007/s10151-018-1756-7

Background: Random duodenal biopsy to exclude coeliac disease during upper gastrointestinal endoscopy for the investigation of iron defciency anaemia remains a common procedure, but is expensive and time-consuming. Serological investigation for coeli... Read More about Random duodenal biopsy to exclude coeliac disease as a cause of anaemia is not cost‑efective and should be replaced with universally performed pre‑endoscopy serology in patients on a suspected cancer pathway.

A comprehensive assessment of benign genetic variability for neurodegenerative disorders (2018)
Journal Article
Guerreiro, R., Sassi, C., Gibbs, J., Edsall, C., Hernandez, D., Brown, K., …Bras, J. (2018). A comprehensive assessment of benign genetic variability for neurodegenerative disorders. https://doi.org/10.1101/270686

Over the last few years, as more and more sequencing studies have been performed, it has become apparent that the identification of pathogenic mutations is, more often than not, a complex issue. Here, with a focus on neurodegenerative diseases, we ha... Read More about A comprehensive assessment of benign genetic variability for neurodegenerative disorders.

The Never-Ending Story: Discursive Legitimation in Social Media Dialogue (2018)
Journal Article
Glozer, S. A., Caruana, R., & Hibbert, S. (2019). The Never-Ending Story: Discursive Legitimation in Social Media Dialogue. Organization Studies, 40(5), 625-650. https://doi.org/10.1177/0170840617751006

© The Author(s) 2018. This paper explores the dialogical dimensions of discursive legitimation in social media sites to understand how organisations produce knowledge of legitimacy in concert with their stakeholders. Drawing on the dialogical theorie... Read More about The Never-Ending Story: Discursive Legitimation in Social Media Dialogue.

Limit-cycle oscillatory coexpression of cross-inhibitory transcription factors: a model mechanism for lineage promiscuity (2018)
Journal Article
Bokes, P., & King, J. R. (in press). Limit-cycle oscillatory coexpression of cross-inhibitory transcription factors: a model mechanism for lineage promiscuity. Mathematical Medicine and Biology, https://doi.org/10.1093/imammb/dqy003

Lineage switches are genetic regulatory motifs that govern and maintain the commitment of a developing cell to a particular cell fate. A canonical example of a lineage switch is the pair of transcription factors PU.1 and GATA-1, of which the former i... Read More about Limit-cycle oscillatory coexpression of cross-inhibitory transcription factors: a model mechanism for lineage promiscuity.

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks (2018)
Journal Article
Abeysuriya, R. G., Hadida, J., Sotiropoulos, S. N., Jbabdi, S., Becker, R., Hunt, B. A., …Woolrich, M. W. (in press). A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks. PLoS Computational Biology, 14(2), Article e1006007. https://doi.org/10.1371/journal.pcbi.1006007

Over long timescales, neuronal dynamics can be robust to quite large perturbations, such as changes in white matter connectivity and grey matter structure through processes including learning, aging, development and certain disease processes. One pos... Read More about A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks.

Funding constraints and liquidity in two-tiered OTC markets (2018)
Journal Article
Benos, E., & Žikeš, F. (2018). Funding constraints and liquidity in two-tiered OTC markets. Journal of Financial Markets, 39, 24-43. https://doi.org/10.1016/j.finmar.2018.01.002

Using primary dealer transactional data from the government bond (gilt) market in the United Kingdom, we identify a new channel through which dealer funding constraints may impair liquidity in two-tiered OTC markets. The key finding is that funding c... Read More about Funding constraints and liquidity in two-tiered OTC markets.

An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion (2018)
Journal Article
Sabbadin, F., Hemsworth, G. R., Ciano, L., Henrissat, B., Dupree, P., Tryfona, T., …McQueen-Mason, S. J. (2018). An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion. Nature Communications, 9, Article 756. https://doi.org/10.1038/s41467-018-03142-x

Thermobia domestica belongs to an ancient group of insects and has a remarkable ability to digest crystalline cellulose without microbial assistance. By investigating the digestive proteome of Thermobia, we have identified over 20 members of an uncha... Read More about An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion.

Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America (2018)
Working Paper
Meyer-Sahling, J., Schuster, C., & Sass Mikkelsen, K. Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America

Civil servants are central to effective governance in developing countries. They deliver essential services to citizens, commission infrastructure, regulate economic activity and engage in diplomacy with foreign countries – to name just a few tasks.... Read More about Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America.

Insurgent posthumanism (2018)
Book
PAPADOPOULOS, D. (2018). Insurgent posthumanism. In Posthuman glossary, 204-207. London: Bloomsbury Publishing

Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent (2018)
Journal Article
Taylor, C. H., Wanelik, K. M., Friberg, I. M., Lowe, A., Hall, A. J., Ralli, C., …Bradley, J. E. (2018). Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent. International Journal for Parasitology, 48(6), 463-471. https://doi.org/10.1016/j.ijpara.2017.11.006

In contrast to the conditions in most laboratory studies, wild animals are routinely challenged by multiple infections at once, and these infections can interact in complex ways. This means that the impact of a parasite on its host’s physiology and f... Read More about Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent.

Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach (2018)
Journal Article
Viljanto, M., Hillyer, L., Hincks, P., Pearce, C., & Paine, S. (2018). Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach. Journal of Veterinary Pharmacology and Therapeutics, 41(3), 469-475. https://doi.org/10.1111/jvp.12491

Medication and doping control has been established in horseracing to ensure the integrity of the sport and the welfare of the horses. This ensures that horses do not compete under the influence of any drugs, including omeprazole, a therapeutic medica... Read More about Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach.