All Outputs (65)

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis (2018)
Journal Article
Friedman, S. L., Ratziu, V., Harrison, S. A., Abdelmalek, M. F., Aithal, G. P., Caballeria, J., …Lefebvre, E. (2018). A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis. Hepatology, 67(5), https://doi.org/10.1002/hep.29477

The aim of this study was to evaluate cenicriviroc (CVC), a dual antagonist of C-C chemokine receptor types 2 and 5, for treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. A randomized, double-blind, multinational phase 2b study e... Read More about A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis.

Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis (2018)
Journal Article
Rollins, K. E., Javanmard-Emamghissi, H., & Lobo, D. N. (in press). Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis. World Journal of Gastroenterology, 24(4), https://doi.org/10.3748/wjg.v24.i4.519

AIM: To analyse the effect of mechanical bowel preparation vs no mechanical bowel preparation on outcome in patients undergoing elective colorectal surgery. METHODS: Meta-analysis of randomised controlled trials and observational studies comparing a... Read More about Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis.

Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements (2018)
Journal Article
Delahay, R. M., Croxall, N. J., & Stephens, A. D. (in press). Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements. Mobile DNA, 9(5), https://doi.org/10.1186/s13100-018-0109-4

Background: The genome of the gastric pathogen Helicobacter pylori is characterised by considerable variation of both gene sequence and content, much of which is contained within three large genomic islands comprising the cag pathogenicity island (ca... Read More about Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements.

A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink (2018)
Journal Article
Crooks, C. J., West, J., & Jepson, P. (2018). A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink. Clinical Epidemiology, 2018:10, https://doi.org/10.2147/CLEP.S147535

Purpose: The CirCom score has been developed from Danish data as a specific measure of comorbidity for cirrhosis to predict all-cause mortality. We compared its performance with the Charlson Comorbidity Index (CCI) in an English cirrhosis population.... Read More about A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink.

Consensus on Training and Implementation of Enhanced Recovery After Surgery: A Delphi Study (2018)
Journal Article
Francis, N. K., Walker, T., Carter, F., Hübner, M., Balfour, A., Jakobsen, D. H., …Ljungqvist, O. (2018). Consensus on Training and Implementation of Enhanced Recovery After Surgery: A Delphi Study. World Journal of Surgery, 42(7), 1919–1928. https://doi.org/10.1007/s00268-017-4436-2

Background Enhanced Recovery After Surgery (ERAS) is widely accepted in current surgical practice due to its positive impact on patient outcomes. The successful implementation of ERAS is chal-lenging and compliance with protocols varies widely. Cont... Read More about Consensus on Training and Implementation of Enhanced Recovery After Surgery: A Delphi Study.