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All Outputs (101)

Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II (2018)
Journal Article
Wu, D., Hu, Q., Tan, B., Rose, P., Zhu, D., & Zhu, Y. Z. (2018). Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II. Redox Biology, 19, 250-262. https://doi.org/10.1016/j.redox.2018.08.008

Aims: Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays a critical role in the development of heart failure and in the induction of myocardial mitochondrial injury. Recent evidence has shown that hydrogen sulfide (H2S), produced by the enzym... Read More about Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II.

Distinct branches of the N‐end rule pathway modulate the plant immune response (2018)
Journal Article
Vicente, J., Mendiondo, G. M., Pauwels, J., Pastor, V., Izquierdo, Y., Naumann, C., …Holdsworth, M. J. (2019). Distinct branches of the N‐end rule pathway modulate the plant immune response. New Phytologist, 221(2), 988-1000. https://doi.org/10.1111/nph.15387

© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles. Here we explored the role of the N-end rule... Read More about Distinct branches of the N‐end rule pathway modulate the plant immune response.

Anthropogenic environmental drivers of antimicrobial resistance in wildlife (2018)
Journal Article
Swift, B. M., Bennett, M., Waller, K., Dodd, C., Murray, A., Gomes, R. L., …Arnold, K. E. (2019). Anthropogenic environmental drivers of antimicrobial resistance in wildlife. Science of the Total Environment, 649, 12-20. https://doi.org/10.1016/j.scitotenv.2018.08.180

The isolation of antimicrobial resistant bacteria (ARB) from wildlife living adjacent to humans has led to the suggestion that such antimicrobial resistance (AMR) is anthropogenically driven by exposure to antimicrobials and ARB. However, ARB have al... Read More about Anthropogenic environmental drivers of antimicrobial resistance in wildlife.

A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation (2018)
Journal Article
Bhosale, R., Boudolf, V., Cuevas, F., Lu, R., Eekhout, T., Hu, Z., …De Veylder, L. (2018). A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation. Plant Cell, 30(10), 2330-2351. https://doi.org/10.1105/tpc.17.00983

© 2018 ASPB. Somatic polyploidy caused by endoreplication is observed in arthropods, molluscs, and vertebrates but is especially prominent in higher plants, where it has been postulated to be essential for cell growth and fate maintenance. However, a... Read More about A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation.

The establishment of a marine focused biorefinery for bioethanol production using seawater and a novel marine yeast strain (2018)
Journal Article
Zaky, A. S., Greetham, D., Tucker, G. A., & Du, C. (2018). The establishment of a marine focused biorefinery for bioethanol production using seawater and a novel marine yeast strain. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-30660-x

Current technologies for bioethanol production rely on the use of freshwater for preparing the fermentation media and use yeasts of a terrestrial origin. Life cycle assessment has suggested that between 1,388 to 9,812 litres of freshwater are consume... Read More about The establishment of a marine focused biorefinery for bioethanol production using seawater and a novel marine yeast strain.

The impact of nitrogen gas flushing on the stability of seasonings: volatile compounds and sensory perception of cheese & onion seasoned potato crisps (2018)
Journal Article
Agarwal, D., Mui, L., Aldridge, E., Mottram, R., McKinney, J., & Fisk, I. D. (2018). The impact of nitrogen gas flushing on the stability of seasonings: volatile compounds and sensory perception of cheese & onion seasoned potato crisps. Food and Function, 9(9), 4730-4741. https://doi.org/10.1039/c8fo00817e

The impact of natural cheese and onion seasoning on the sensory perception and shelf life stability of potato crisps was studied. This study was carried out to evaluate the impact of nitrogen (N2) gas flushing on the shelf-life stability and sensory... Read More about The impact of nitrogen gas flushing on the stability of seasonings: volatile compounds and sensory perception of cheese & onion seasoned potato crisps.

Hidden variation in polyploid wheat drives local adaptation (2018)
Journal Article
Gardiner, L., Joynson, R., Omony, J., Rusholme-Pilcher, R., Olohan, L., Lang, D., …Hall, A. (2018). Hidden variation in polyploid wheat drives local adaptation. Genome Research, 28(9), 1319-1332. https://doi.org/10.1101/gr.233551.117

Wheat has been domesticated into a large number of agricultural environments and has the ability to adapt to diverse environments. To understand this process, we survey genotype, repeat content, and DNA methylation across a bread wheat landrace colle... Read More about Hidden variation in polyploid wheat drives local adaptation.

Use of the extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans (2018)
Journal Article
Channell, G. A., Adams, G. G., Lu, Y., Gillis, R. B., Dinu, V., Grundy, M. M., …Harding, S. E. (2018). Use of the extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans. Scientific Reports, 8(1), Article 11809. https://doi.org/10.1038/s41598-018-29997-0

Beta 1–3, 1–4 glucans (“beta-glucans”) are one of the key components of the cell wall of cereals, complementing the main structural component cellulose. Beta-glucans are also an important source of soluble fibre in foods containing oats with claims o... Read More about Use of the extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans.

The Svedberg Lecture 2017. From nano to micro: the huge dynamic range of the analytical ultracentrifuge for characterizing the sizes, shapes and interactions of molecules and assemblies in biochemistry and polymer science (2018)
Journal Article
Harding, S. E., Wakefield, J., Gillis, R., Adams, G., & McQueen, C. (2018). The Svedberg Lecture 2017. From nano to micro: the huge dynamic range of the analytical ultracentrifuge for characterizing the sizes, shapes and interactions of molecules and assemblies in biochemistry and polymer science. European Biophysics Journal, 47(7), 697–707. https://doi.org/10.1007/s00249-018-1290-6

The analytical ultracentrifuge (AUC) invented by T. Svedberg has now become an extremely versatile and diverse tool in Biochemistry and Polymer Science for the characterisation of the sizes, shapes and interactions of particles ranging in size from a... Read More about The Svedberg Lecture 2017. From nano to micro: the huge dynamic range of the analytical ultracentrifuge for characterizing the sizes, shapes and interactions of molecules and assemblies in biochemistry and polymer science.

Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth (2018)
Journal Article
Brown, D. M., Jones, S., Daniel, Z. C., Brearley, M. C., Lewis, J. E., Ebling, F. J., …Brameld, J. M. (2018). Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth. PLoS ONE, 13(7), Article e0201481. https://doi.org/10.1371/journal.pone.0201481

Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), wo... Read More about Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth.

Parameter inference to motivate asymptotic model reduction: an analysis of the gibberellin biosynthesis pathway (2018)
Journal Article
Band, L. R., & Preston, S. P. (2018). Parameter inference to motivate asymptotic model reduction: an analysis of the gibberellin biosynthesis pathway. Journal of Theoretical Biology, 457, 66-78. https://doi.org/10.1016/j.jtbi.2018.05.028

Developing effective strategies to use models in conjunction with experimental data is essential to understand the dynamics of biological regulatory networks. In this study, we demonstrate how combining parameter estimation with asymptotic analysis c... Read More about Parameter inference to motivate asymptotic model reduction: an analysis of the gibberellin biosynthesis pathway.

Impact of environmental radiation on the health and reproductive status of fish from Chernobyl (2018)
Journal Article
Lerebours, A., Gudkov, D., Nagorskaya, L., Kaglyan, A., Rizewski, V., Leshchenko, A., …Smith, J. T. (2018). Impact of environmental radiation on the health and reproductive status of fish from Chernobyl. Environmental Science and Technology, 52(16), 9442-9450. https://doi.org/10.1021/acs.est.8b02378

© 2018 American Chemical Society. Aquatic organisms at Chernobyl have now been chronically exposed to environmental radiation for three decades. The biological effects of acute exposure to radiation are relatively well documented, but much less is kn... Read More about Impact of environmental radiation on the health and reproductive status of fish from Chernobyl.

Uncovering the hidden half of plants using new advances in root phenotyping (2018)
Journal Article
Atkinson, J. A., Pound, M. P., Bennett, M. J., & Wells, D. M. (2019). Uncovering the hidden half of plants using new advances in root phenotyping. Current Opinion in Biotechnology, 55, 1-8. https://doi.org/10.1016/j.copbio.2018.06.002

© 2018 The Authors Major increases in crop yield are required to keep pace with population growth and climate change. Improvements to the architecture of crop roots promise to deliver increases in water and nutrient use efficiency but profiling the r... Read More about Uncovering the hidden half of plants using new advances in root phenotyping.

Root-derived CO2 flux from a tropical peatland (2018)
Journal Article
Girkin, N., Turner, B., Ostle, N., & Sjögersten, S. (2018). Root-derived CO2 flux from a tropical peatland. Wetlands Ecology and Management, 26(5), 985-991. https://doi.org/10.1007/s11273-018-9617-8

Tropical peatlands release significant quantities of greenhouse gases to the atmosphere, yet the relative contributions of heterotrophic and autotrophic respiration to net CO2 fluxes remains sparsely quantified. We used a combination of in situ trenc... Read More about Root-derived CO2 flux from a tropical peatland.

Investigating the environmental interpretation of oxygen and carbon isotope data from whole and fragmented bivalve shells (2018)
Journal Article
Lacey, J., Leng, M., Peckover, E., Dean, J., Wilke, T., Francke, A., …Wagner, B. (2018). Investigating the environmental interpretation of oxygen and carbon isotope data from whole and fragmented bivalve shells. Quaternary Science Reviews, 194, https://doi.org/10.1016/j.quascirev.2018.06.025

Sclerochronological data from whole bivalve shells have been used extensively to derive palaeoenvironmental information. However, little is known about the relevance of shell fragments more commonly preserved in the sediment record. Here, we investig... Read More about Investigating the environmental interpretation of oxygen and carbon isotope data from whole and fragmented bivalve shells.

Exploring drivers of litter decomposition in a greening Arctic: results from a transplant experiment across a tree-line (2018)
Journal Article
Parker, T. C., Sanderman, J., Holden, R. D., Blume-Werry, G., Sjögersten, S., Large, D., …Wookey, P. A. (2018). Exploring drivers of litter decomposition in a greening Arctic: results from a transplant experiment across a tree-line. Ecology, 99(10), 2284-2294. https://doi.org/10.1002/ecy.2442

Decomposition of plant litter is a key control over carbon (C) storage in the soil. The biochemistry of the litter being produced, the environment in which the decomposition is taking place, and the community composition and metabolism of the decompo... Read More about Exploring drivers of litter decomposition in a greening Arctic: results from a transplant experiment across a tree-line.

Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7 (2018)
Journal Article
Ricachenevsky, F. K., Punshon, T., Lee, S., Oliveira, B. H. N., Trenz, T. S., Maraschin, F. D. S., …Guerinot, M. L. (in press). Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7. Frontiers in Plant Science, 9, https://doi.org/10.3389/fpls.2018.00865

Iron (Fe) and zinc (Zn) are essential micronutrients required for proper development in both humans and plants. Rice (Oryza sativa L.) grains are the staple food for nearly half of the world’s population, but a poor source of metals such as Fe and Zn... Read More about Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7.

Holocene atmospheric circulation in the central North Pacific: a new terrestrial diatom and δ18O dataset from the Aleutian Islands (2018)
Journal Article
Bailey, H. L., Kaufman, D. S., Sloane, H. J., Hubbard, A. L., Henderson, A. C., Leng, M. J., …Welker, J. M. (2018). Holocene atmospheric circulation in the central North Pacific: a new terrestrial diatom and δ18O dataset from the Aleutian Islands. Quaternary Science Reviews, 194, 27-38. https://doi.org/10.1016/j.quascirev.2018.06.027

The North Pacific is a zone of cyclogenesis that modulates synoptic-scale atmospheric circulation, yet there is a paucity of instrumental and paleoclimate data to fully constrain its long-term state and variability. We present the first Holocene oxyg... Read More about Holocene atmospheric circulation in the central North Pacific: a new terrestrial diatom and δ18O dataset from the Aleutian Islands.

Interaction between contrasting rice genotypes and soil physical conditions induced by hydraulic stresses typical of alternate wetting and drying irrigation of soil (2018)
Journal Article
Fang, H., Zhou, H., Norton, G. J., Price, A. H., Raffan, A. C., Mooney, S. J., …Hallett, P. D. (2018). Interaction between contrasting rice genotypes and soil physical conditions induced by hydraulic stresses typical of alternate wetting and drying irrigation of soil. Plant and Soil, 430(1-2), 233-243. https://doi.org/10.1007/s11104-018-3715-5

© 2018, The Author(s). Background and aims: Alternate wetting and drying (AWD) saves water in paddy rice production but could influence soil physical conditions and root growth. This study investigated the interaction between contrasting rice genotyp... Read More about Interaction between contrasting rice genotypes and soil physical conditions induced by hydraulic stresses typical of alternate wetting and drying irrigation of soil.