All Outputs (2)

Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide induced hyponatremia (2018)
Journal Article
Channavajjhala, S. K., Bramley, R., Peltz, T., Oosthuyzen, W., Jia, W., Kinnear, S., …Glover, M. (2019). Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide induced hyponatremia. Kidney International Reports, 4(1), 139-147. https://doi.org/10.1016/j.ekir.2018.09.011

Introduction Thiazide diuretics are amongst the most widely used anti-hypertensive medicines worldwide. Thiazide-Induced Hyponatremia (TIH) is one of their most clinically significant adverse effects. A priori TIH must result from excessive saliur... Read More about Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide induced hyponatremia.

Clinical and molecular features of thiazide-induced hyponatremia (2018)
Journal Article
Nadal, J., Channavajjhala, S. K., Jia, W., Clayton, J., Hall, I. P., & Glover, M. (2018). Clinical and molecular features of thiazide-induced hyponatremia. Current Hypertension Reports, 20(4), Article 31

Hypertension affects more than 30% of the world’s adult population and thiazide (and thiazide-like) diuretics are amongst the most widely used, effective and least costly treatments available, with all-cause mortality benefits equivalent to ACE inhib... Read More about Clinical and molecular features of thiazide-induced hyponatremia.