All Outputs (3)

The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse (2018)
Journal Article
Shibany, K. A., Tötemeyer, S., Pratt, S. L., & Paine, S. W. (2018). The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse. Xenobiotica, 48(12), 1237-1244. https://doi.org/10.1080/00498254.2017.1413263

Scaling factor values for the in vitro-in vivo extrapolation of hepatic metabolic clearance for xenobiotics have not yet been determined in horses. Scaling factors were determined by comparing the total protein and or CYP P450 content in microsomes a... Read More about The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse.

Novel inflammatory cell infiltration scoring system to investigate healthy and footrot affected ovine interdigital skin (2018)
Journal Article
Agbaje, M., Rutland, C. S., Maboni, G., Blanchard, A., Bexon, M., Stewart, C., …Totemeyer, S. (2018). Novel inflammatory cell infiltration scoring system to investigate healthy and footrot affected ovine interdigital skin. PeerJ, 6, Article e5097. https://doi.org/10.7717/peerj.5097

Ovine footrot is a degenerative disease of sheep feet leading to the separation of hoofhorn from the underlying skin and lameness. This study quantitatively examined histological features of the ovine interdigital skin as well as their relationship w... Read More about Novel inflammatory cell infiltration scoring system to investigate healthy and footrot affected ovine interdigital skin.

The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus (2018)
Journal Article
Blanchard, A. M., Jolley, K. A., Maiden, M. C., Coffey, T. J., Maboni, G., Staley, C. E., …Tötemeyer, S. (in press). The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus. Frontiers in Microbiology, 9, Article 551. https://doi.org/10.3389/fmicb.2018.00551

Dichelobacter nodosus (D. nodosus) is the causative pathogen of ovine footrot, a disease that has a significant welfare and financial impact on the global sheep industry. Previous studies into the phylogenetics of D. nodosus have focused on Australia... Read More about The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus.