All Outputs (2)

Effect of loading history on airway smooth muscle cell-matrix adhesions (2018)
Journal Article
Irons, L., Owen, M. R., O'Dea, R. D., & Brook, B. S. (2018). Effect of loading history on airway smooth muscle cell-matrix adhesions. Biophysical Journal, 114(11), 2679-2690. https://doi.org/10.1016/j.bpj.2018.04.026

Integrin-mediated adhesions between airway smooth muscle (ASM) cells and the extracellular matrix (ECM) regulate how contractile forces generated within the cell are transmitted to its external environment. Environmental cues are known to influence t... Read More about Effect of loading history on airway smooth muscle cell-matrix adhesions.

Capturing the dynamics of a hybrid multiscale cancer model with a continuum model (2018)
Journal Article
Joshi, T. V., Avitabile, D., & Owen, M. R. (2018). Capturing the dynamics of a hybrid multiscale cancer model with a continuum model. Bulletin of Mathematical Biology, 80(6), 1435–1475. https://doi.org/10.1007/s11538-018-0406-6

Cancer is a complex disease involving processes at spatial scales from sub-cellular, like cell signalling, to tissue scale, such as vascular network formation. A number of multiscale models have been developed to study the dynamics that emerge from t... Read More about Capturing the dynamics of a hybrid multiscale cancer model with a continuum model.