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All Outputs (14)

In vitro evaluation of electrospun blends of gelatin and PCL for application as a partial thickness corneal graft (2018)
Journal Article
Rose, J., Sidney, L., Patient, J., White, L., Dua, H., El Haj, A., …Rose, F. (2018). In vitro evaluation of electrospun blends of gelatin and PCL for application as a partial thickness corneal graft. Journal of Biomedical Materials Research Part A, 107(4), 828-838. https://doi.org/10.1002/jbm.a.36598

The advent of innovative surgical procedures utilizing partial thickness corneal grafts has created a need for the development of synthetic implants to recreate corneal stromal tissue. This work evaluates electrospun gelatin and polycaprolactone (PCL... Read More about In vitro evaluation of electrospun blends of gelatin and PCL for application as a partial thickness corneal graft.

Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche (2018)
Working Paper
Prina, E., Sidney, L., Tromayer, M., Moore, J., Liska, R., Bertolin, M., …Rose, F. R. Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche

Stem cells within epithelial tissues reside in anatomical structures known as crypts that are known to contribute to the mechanical and chemical milieu important for function. To date, epithelial stem cell therapies have largely ignored the niche and... Read More about Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche.

Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus (2018)
Journal Article
Said, D. G., Ross, A. R., Messina, M., Mohammed, I., & Dua, H. (2018). Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus. Eye, doi:10.1038/s41433-018-0211-3

Corneal collagen cross-linking (CXL) is the only treatment that delays or arrests progression of keratoconus. CXL is a safe procedure with few complications. CXL protocols vary depending on time and energy used but all are safe and effective. Variati... Read More about Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus.

In vivo microscopic and optical coherence tomography classification of neurotrophic keratopathy (2018)
Journal Article
Mastropasqua, L., Nubile, M., Lanzini, M., Calienno, R., & Dua, H. S. (2019). In vivo microscopic and optical coherence tomography classification of neurotrophic keratopathy. Journal of Cellular Physiology, 234(5), 6108-6115. https://doi.org/10.1002/jcp.27345

© 2018 Wiley Periodicals, Inc. Neurotrophic keratopathy (NK) is a rare degenerative corneal disorder characterized by instability of epithelial integrity with consequent epithelial defects that can worsen up to persistent epithelial defects with stro... Read More about In vivo microscopic and optical coherence tomography classification of neurotrophic keratopathy.

Epiretinal Membrane Surgery Outcomes in Eyes with Subretinal Drusenoid Deposits: A Case Control Study (2018)
Journal Article
Wilde, C., Awad, M., Dua, H., Gandhewar, R., Chen, H., & Amoaku, W. M. (2018). Epiretinal Membrane Surgery Outcomes in Eyes with Subretinal Drusenoid Deposits: A Case Control Study. Ophthalmology Retina, 2(12), 1218-1226. https://doi.org/10.1016/j.oret.2018.06.009

© 2018 Purpose: To evaluate outcomes of epiretinal membrane (ERM) surgery in eyes with subretinal drusenoid deposits (SRDDs) and to compare them with those with isolated ERM. Design: Retrospective case-control study of consecutive patients who underw... Read More about Epiretinal Membrane Surgery Outcomes in Eyes with Subretinal Drusenoid Deposits: A Case Control Study.

Healing of autologous conjunctival grafts in pterygium surgery (2018)
Journal Article
Ghoz, N., Elalfy, M., Said, D., & Dua, H. (2018). Healing of autologous conjunctival grafts in pterygium surgery. Acta Ophthalmologica, 96(8), e979-e988. https://doi.org/10.1111/aos.13794

Purpose To temporally study the healing of conjunctival autografts in consecutive patients following pterygium surgery. Methods A case?cohort observational study. Thirty?two eyes of 28 patients who underwent pterygium surgery were included. All... Read More about Healing of autologous conjunctival grafts in pterygium surgery.

Lamellar keratoplasty techniques (2018)
Journal Article
Dua, H. S., Singh, N., & Said, D. (2018). Lamellar keratoplasty techniques. Indian Journal of Ophthalmology, 66(9), 1239-1250. https://doi.org/10.4103/ijo.IJO_95_18

© 2018 Indian Journal of Ophthalmology. Lamellar keratoplasty (LK) has revolutionized corneal graft surgery in several ways. Deep anterior LK (DALK) has eliminated risk of failure due to endothelial rejection. Endothelial keratoplasty (EK) has almost... Read More about Lamellar keratoplasty techniques.

Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling (2018)
Journal Article
Mohammed, I., Ross, A. R., Britton, J. O., Said, D. G., & Dua, H. S. (2018). Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling. American Journal of Ophthalmology, 194, 16-25. https://doi.org/10.1016/j.ajo.2018.07.001

Purpose Descemet membrane endothelial keratoplasty (DMEK) and pre-Descemet endothelial keratoplasty (PDEK) tissues always scroll with the endothelial cells (EC) outside. We designed a study to understand the reason for this behavior. Design... Read More about Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling.

Neurotrophic keratopathy (2018)
Journal Article
Dua, H. S., Said, D. G., Messmer, E. M., Rolando, M., Benitez-del-Castillo, J. M., Hossain, P. N., …Baudouin, C. (2018). Neurotrophic keratopathy. Progress in Retinal and Eye Research, 66, 107-131. https://doi.org/10.1016/j.preteyeres.2018.04.003

Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to frank epithelial defect with or without stromal ulceration (melting) is associated with reduced or absent corneal sensations. Sensory nerves serve nociceptor... Read More about Neurotrophic keratopathy.

Deep anterior lamellar keratoplasty: dissection plane with viscoelastic and air can be different (2018)
Journal Article
Ross, A. R., Said, D. G., El-Amin, A., Altaan, S., Cabrerizo, J., Nubile, M., …Dua, H. S. (2018). Deep anterior lamellar keratoplasty: dissection plane with viscoelastic and air can be different. British Journal of Ophthalmology, 102(12), 1646-1652. https://doi.org/10.1136/bjophthalmol-2017-311349

Aims: To investigate and define the nature of big bubbles (BB) formed by injection of viscoelastic in deep anterior lamellar keratoplasty. Methods: Intrastromal injections of 0.1 and 0.3 mL of sodium hyaluronate 1.2% and 0.6% were made into sclera... Read More about Deep anterior lamellar keratoplasty: dissection plane with viscoelastic and air can be different.

Early results on the use of chitosan-N-acetylcysteine (Lacrimera®) in the management of dry eye disease of varied etiology (2018)
Journal Article
Messina, M., & Dua, H. S. (2019). Early results on the use of chitosan-N-acetylcysteine (Lacrimera®) in the management of dry eye disease of varied etiology. International Ophthalmology, 39(3), 693-696. https://doi.org/10.1007/s10792-018-0843-0

Purpose To evaluate the effect of once daily administration of chitosan-N-acetylcysteine (Lacrimera®) in the management of dry eye disease (DED). Methods Eighteen patients (3 male, 15 female) aged 25–86 years (mean 61.1) and suffering from moder... Read More about Early results on the use of chitosan-N-acetylcysteine (Lacrimera®) in the management of dry eye disease of varied etiology.