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The loss of α- and β-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing (2018)
Journal Article
Labisso, W., Raulin, A., Nwidu, L., Kocon, A., Wayne, D., Erdozain, A., …Carter, W. (2018). The loss of α- and β-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing. Brain Sciences, 8(9), Article 175. https://doi.org/10.3390/brainsci8090175

Repetitive excessive alcohol intoxication leads to neuronal damage and brain shrinkage. We examined cytoskeletal protein expression in human post-mortem tissue from Brodmann’s area 9 of the prefrontal cortex (PFC). Brain samples from 44 individuals w... Read More about The loss of α- and β-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing.

Alleviation of carbon tetrachloride-induced hepatocellular damage and oxidative stress with a leaf extract of Glyphae brevis (Tiliaceae) (2018)
Journal Article
Lucky, L., Yibali, O., Ekramy, E., & Wayne, C. (2018). Alleviation of carbon tetrachloride-induced hepatocellular damage and oxidative stress with a leaf extract of Glyphae brevis (Tiliaceae). Journal of Basic and Clinical Physiology and Pharmacology, 29(6), 609-619. https://doi.org/10.1515/jbcpp-2017-0058

Background Glyphae brevis leaf is reported in ethnomedicine as a treatment for hepatitis and jaundice; however, no studies have hitherto investigated the mechanistic basis of these claims. Methods A hepato-protective role of G. brevis hydromet... Read More about Alleviation of carbon tetrachloride-induced hepatocellular damage and oxidative stress with a leaf extract of Glyphae brevis (Tiliaceae).

In vitro anti-cholinesterase and antioxidant activity of extracts of Moringa oleifera plants from Rivers State, Niger Delta, Nigeria (2018)
Journal Article
Nwidu, L. L., Elmorsy, E., Aprioku, J., Siminialayi, I., & Carter, W. (2018). In vitro anti-cholinesterase and antioxidant activity of extracts of Moringa oleifera plants from Rivers State, Niger Delta, Nigeria. Medicines, 5(3), Article 71. https://doi.org/10.3390/medicines5030071

This study evaluated Moringa oleifera extracts from two locations in Niger Delta for in vitro anti-cholinesterase and antioxidant activities. Methanolic, aqueous and ethanolic extracts of Moringa oleifera were evaluated for inhibition of acetylcholin... Read More about In vitro anti-cholinesterase and antioxidant activity of extracts of Moringa oleifera plants from Rivers State, Niger Delta, Nigeria.

Hepatoprotective effect of hydromethanolic leaf extract of Musanga cecropioides (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress (2018)
Journal Article
Nwidu, L. L., Oboma, Y. I., Elmorsy, E., & Carter, W. G. (2018). Hepatoprotective effect of hydromethanolic leaf extract of Musanga cecropioides (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress. Journal of Taibah University Medical Sciences, 13(4), https://doi.org/10.1016/j.jtumed.2018.04.006

Objective: Natural antioxidant products are gaining popularity as treatments for various pathological liver injuries. Musanga cecropioides (Urticaceae) leaf extract is used in ethnomedicine for the management of jaundice and other hepatic ailments in... Read More about Hepatoprotective effect of hydromethanolic leaf extract of Musanga cecropioides (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress.

In vitro anti-cholinesterase and anti-oxidant activity of three standardised polyherbal products used for memory enhancing in ethnomedicine of South-East Nigeria (2018)
Journal Article
Nwidu, L. L., Elmorsy, E., & Carter, W. (2018). In vitro anti-cholinesterase and anti-oxidant activity of three standardised polyherbal products used for memory enhancing in ethnomedicine of South-East Nigeria. Malaysian Journal of Medical Sciences, 25(2), https://doi.org/10.21315/mjms2018.25.2.4

Background: Polyherbal standardised extracts used in ethnomedicine of Eastern Nigeria for memory improvements were evaluated for anti-cholinesterases and anti-oxidant properties. Methods: Anti-cholinesterase, anti-oxidant, and total phenolic and f... Read More about In vitro anti-cholinesterase and anti-oxidant activity of three standardised polyherbal products used for memory enhancing in ethnomedicine of South-East Nigeria.

Hepatoprotective and antioxidant activities of Spondias mombin leaf and stem extracts against carbon tetrachloride-induced hepatotoxicity (2018)
Journal Article
Nwidu, L. L., Elmorsy, E., Yibala, O. I., & Carter, W. (2018). Hepatoprotective and antioxidant activities of Spondias mombin leaf and stem extracts against carbon tetrachloride-induced hepatotoxicity. Journal of Taibah University Medical Sciences, 13(3), https://doi.org/10.1016/j.jtumed.2018.03.006

Objective Spondias mombin L. is a tree used in folk medicine in Nigeria for the treatment of hepatitis. This study was carried out to comparatively evaluate the hepatoprotective and antioxidant effects of S. mombin leaf and stem (SML and SMS) meth... Read More about Hepatoprotective and antioxidant activities of Spondias mombin leaf and stem extracts against carbon tetrachloride-induced hepatotoxicity.