All Outputs (4)

Contribution of the alkylquinolone quorum sensing system to the interaction of Pseudomonas aeruginosa with bronchial epithelial cells. (2018)
Journal Article
Liu, Y., Hussain, F., Negm, O., Pavia, A., Halliday, N., Frédéric Dubern, J., …Martínez-Pomares, L. (2018). Contribution of the alkylquinolone quorum sensing system to the interaction of Pseudomonas aeruginosa with bronchial epithelial cells. Frontiers in Microbiology, 9, Article 3018. https://doi.org/10.3389/fmicb.2018.03018

Pseudomonas aeruginosa causes infections in patients with compromised epithelial 32 barrier function. Multiple virulence factors produced by P. aeruginosa are controlled 33 by quorum sensing (QS) via 2-alkyl-4(1H)-quinolone (AQ) signal molecules. Her... Read More about Contribution of the alkylquinolone quorum sensing system to the interaction of Pseudomonas aeruginosa with bronchial epithelial cells..

Tobacco smoke and nicotine suppress expression of activating signaling molecules in human dendritic cells (2018)
Journal Article
Alkhattabi, N., Todd, I., Negm, O., Tighe, P. J., & Fairclough, L. C. (2018). Tobacco smoke and nicotine suppress expression of activating signaling molecules in human dendritic cells. Toxicology Letters, 299, 40-46. https://doi.org/10.1016/j.toxlet.2018.09.002

Cigarette smoke has significant toxic effects on the immune system, and increases the risk of developing autoimmune diseases; one immunosuppressive effect of cigarette smoke is that it inhibits the T cell-stimulating, immunogenic properties of myeloi... Read More about Tobacco smoke and nicotine suppress expression of activating signaling molecules in human dendritic cells.

Highly sensitive label-free antibody detection using a long period fibre grating sensor (2018)
Journal Article
Liu, L., Marques, L., Correia, R., Morgan, S. P., Lee, S., Tighe, P. J., …Korposh, S. (2018). Highly sensitive label-free antibody detection using a long period fibre grating sensor. Sensors and Actuators B: Chemical, 271, 24-32. https://doi.org/10.1016/j.snb.2018.05.109

An optical fibre long period grating (LPG) biosensor is appealing in the detection of biomolecules because of the high sensitivity, label-free and real-time measurement. The miniaturized size, ability of remote sensing and immunity to electromagnetic... Read More about Highly sensitive label-free antibody detection using a long period fibre grating sensor.

Characterization of behavioral, signaling and cytokine alterations in a rat neurodevelopmental model for schizophrenia, and their reversal by the 5-HT6 receptor antagonist SB-399885 (2018)
Journal Article
Shortall, S. E., Negm, O. H., Fowler, M., Fairclough, L. C., Tighe, P. J., Wigmore, P. M., & King, M. (2018). Characterization of behavioral, signaling and cytokine alterations in a rat neurodevelopmental model for schizophrenia, and their reversal by the 5-HT6 receptor antagonist SB-399885. Molecular Neurobiology, 55(9), https://doi.org/10.1007/s12035-018-0940-0

Post-weaning social isolation of rats produces neuroanatomical, neurochemical and behavioral alterations resembling some core features of schizophrenia. This study examined the ability of the 5-HT? receptor antagonist SB-399885 to reverse isolation-i... Read More about Characterization of behavioral, signaling and cytokine alterations in a rat neurodevelopmental model for schizophrenia, and their reversal by the 5-HT6 receptor antagonist SB-399885.