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Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION2 (2018)
Journal Article
Gibbs, D. J., Tedds, H. M., Labandera, A., Bailey, M., White, M. D., Hartman, S., …Holdsworth, M. J. (2018). Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION2. Nature Communications, 9, Article 5438. https://doi.org/10.1038/s41467-018-07875-7

The polycomb repressive complex 2 (PRC2) regulates epigenetic gene repression in eukaryotes. Mechanisms controlling its developmental specificity and signal-responsiveness are poorly understood. Here, we identify an oxygen-sensitive N-terminal (N-) d... Read More about Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION2.

A regulatory module controlling GA-mediated endosperm cell expansion is critical for seed germination in Arabidopsis (2018)
Journal Article
Sánchez-Montesino, R., Bouza-Morcillo, L., Marquez, J., Ghita, M., Duran-Nebreda, S., Gómez, L., …Oñate-Sánchez, L. (2019). A regulatory module controlling GA-mediated endosperm cell expansion is critical for seed germination in Arabidopsis. Molecular Plant, 12(1), 71-85. https://doi.org/10.1016/j.molp.2018.10.009

A key component of seed germination is the interplay of mechanical forces governing embryo growth and the surrounding restraining endosperm tissue. Endosperm cell separation is therefore thought to play a critical role in the control of this developm... Read More about A regulatory module controlling GA-mediated endosperm cell expansion is critical for seed germination in Arabidopsis.

Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment (2018)
Journal Article
Zhang, H., Gannon, L., Jones, P. D., Rundle, C. A., Hassall, K. L., Gibbs, D. J., …Theodoulou, F. L. (2018). Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment. Scientific Reports, 8(1), Article 15192. https://doi.org/10.1038/s41598-018-33630-5

The Arg/N-end rule pathway of ubiquitin-mediated proteolysis has multiple functions throughout plant development, notably in the transition from dormant seed to photoautotrophic seedling. PROTEOLYSIS6 (PRT6), an N-recognin E3 ligase of the Arg/N-end... Read More about Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment.

Distinct branches of the N‐end rule pathway modulate the plant immune response (2018)
Journal Article
Vicente, J., Mendiondo, G. M., Pauwels, J., Pastor, V., Izquierdo, Y., Naumann, C., …Holdsworth, M. J. (2019). Distinct branches of the N‐end rule pathway modulate the plant immune response. New Phytologist, 221(2), 988-1000. https://doi.org/10.1111/nph.15387

© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles. Here we explored the role of the N-end rule... Read More about Distinct branches of the N‐end rule pathway modulate the plant immune response.

Sumoylation and phosphorylation: hidden and overt links (2018)
Journal Article
Tomanov, K., Nukarinen, E., Vicente, J., Mendiondo, G. M., Winter, N., Nehlin, L., …Bachmair, A. (in press). Sumoylation and phosphorylation: hidden and overt links. Journal of Experimental Botany, https://doi.org/10.1093/jxb/ery167

Post-translational modifications are essential mediators between stimuli from development or the environment and adaptive transcriptional patterns. Recent data allow a first glimpse at how two modifications, phosphorylation and sumoylation, act inter... Read More about Sumoylation and phosphorylation: hidden and overt links.

Finite indentation of highly curved elastic shells (2018)
Journal Article
Pearce, S. P., King, J. R., Steinbrecher, T., Leubner-Metzger, G., Everitt, N. M., & Holdsworth, M. J. (2018). Finite indentation of highly curved elastic shells. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 474(2209), https://doi.org/10.1098/rspa.2017.0482

Experimentally measuring the elastic properties of thin biological surfaces is non-trivial, particularly when they are curved. One technique that may be used is the indentation of a thin sheet of material by a rigid indenter, whilst measuring the app... Read More about Finite indentation of highly curved elastic shells.