Skip to main content

Research Repository

Advanced Search

All Outputs (4)

Brown adipose tissue and glucose homeostasis – the link between climate change and the global rise in obesity and diabetes (2018)
Journal Article
Symonds, M. E., Farhat, G., Aldiss, P., Pope, M., & Budge, H. (2019). Brown adipose tissue and glucose homeostasis – the link between climate change and the global rise in obesity and diabetes. Adipocyte, 8(1), 46-50. https://doi.org/10.1080/21623945.2018.1551689

There is increasing evidence that the global rise in temperature is contributing to the onset of diabetes, which could be mediated by a concomitant reduction in brown fat activity. Brown (and beige) fat are characterised as possessing a unique mitoch... Read More about Brown adipose tissue and glucose homeostasis – the link between climate change and the global rise in obesity and diabetes.

Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy (2018)
Journal Article
Symonds, M. E., Aldiss, P., Pope, M., & Budge, H. (2018). Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy. F1000Research, 7, 1-8. https://doi.org/10.12688/f1000research.14585.1

Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enables the rapid generation of heat and the oxidation of lipids or glucose or both. It is present in small amounts (~15–350 mL) in adult humans. UCP1 is r... Read More about Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy.

Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation (2018)
Journal Article
Fainberg, H. P., Birtwistle, M., Alagal, R., Alhaddad, A., Pope, M., Davies, G., …Symonds, M. E. (2018). Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation. Scientific Reports, 8(1), 1-11. https://doi.org/10.1038/s41598-018-27376-3

Brown adipose tissue (BAT) undergoes pronounced changes after birth coincident with the loss of the BAT-specifc uncoupling protein (UCP)1 and rapid fat growth. The extent to which this adaptation may vary between anatomical locations remains unknown,... Read More about Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation.