All Outputs (2)

Anti-inflammatory potential of thymosin ?4 in the central nervous system: implications for progressive neurodegenerative diseases (2018)
Journal Article
Pardon, M. (2018). Anti-inflammatory potential of thymosin ?4 in the central nervous system: implications for progressive neurodegenerative diseases. Expert Opinion on Biological Therapy, 18(sup1), 165-169. https://doi.org/10.1080/14712598.2018.1486817

Introduction: The actin-sequestering thymosin beta4 (Tβ4) is the most abundant member of the β-thymosins, and is widely expressed in the central nervous system (CNS), but its functions in the healthy and diseased brain are poorly understood. The expr... Read More about Anti-inflammatory potential of thymosin ?4 in the central nervous system: implications for progressive neurodegenerative diseases.

Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons (2018)
Journal Article
Geiszler, P. C., Ugun-Klusek, A., Lawler, K., Pardon, M., Yuchun, D., Bai, L., …Bedford, L. (in press). Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons. Scientific Reports, 8, Article 4833. https://doi.org/10.1038/s41598-018-23155-2

Metabolite profiling is an important tool that may better capture the multiple features of neurodegeneration. With the considerable parallels between mouse and human metabolism, the use of metabolomics in mouse models with neurodegenerative pathology... Read More about Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons.