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All Outputs (6)

The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females (2018)
Journal Article
Herrod, P. J. J., Blackwell, J. E. M., Moss, B. F., Gates, A., Atherton, P. J., Lund, J. N., …Phillips, B. E. (2019). The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females. European Journal of Applied Physiology, 119(3), 645-652. https://doi.org/10.1007/s00421-018-4054-1

PURPOSE: Cardiovascular disease (CVD) is the leading cause of death worldwide. Many risk factors for CVD can be modified pharmacologically; however, uptake of medications is low, especially in asymptomatic people. Exercise is also effective at reduc... Read More about The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females.

Worms in space for outreach on earth: space life science activities for the classroom (2018)
Journal Article
Gaffney, C. J., Pollard, A. K., Deane, C. S., Cooke, M., Balsamo, M., Hewitt, J., …Phillips, B. E. (2018). Worms in space for outreach on earth: space life science activities for the classroom. Gravitational and space research : publication of the American Society for Gravitational and Space Research, 6(2), 74-82

Long term spaceflight is associated with the loss of skeletal muscle mass and function. The Molecular Muscle Experiment (MME) seeks to identify the causes of muscle decline in space and test potential therapies to attenuate this in the microscopic wo... Read More about Worms in space for outreach on earth: space life science activities for the classroom.

A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults (2018)
Journal Article
Din, U., Brook, M., Selby, A. L., Quinlan, J. I., Boereboom, C., Abdullah, H., …Smith, K. (2019). A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults. Clinical Nutrition, 38(5), 2071-2078. https://doi.org/10.1016/j.clnu.2018.09.025

Age-related sarcopenia and dynapenia are associated with frailty and metabolic diseases. Resistance exercise training (RET) adjuvant to evidence-based nutritional intervention(s) have been shown as mitigating strategies. Given that HMB supplementatio... Read More about A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults.

Short-term (less 8 wk) high-intensity interval training in diseased cohorts (2018)
Journal Article
Blackwell, J. E., Doleman, B., Herrod, P., Ricketts, S., Phillips, B. E., Lund, J. N., & Williams, J. P. (2018). Short-term (less 8 wk) high-intensity interval training in diseased cohorts. Medicine and Science in Sports and Exercise, 50(9), 1740–1749. https://doi.org/10.1249/MSS.0000000000001634

Background and Aim: Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High-intensity interval training (HIIT) offers a time-ef... Read More about Short-term (less 8 wk) high-intensity interval training in diseased cohorts.

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease (2018)
Journal Article
Timmons, J. A., Atherton, P. J., Larsson, O., Sood, S., Blokhin, I. O., Brogan, R. J., …Kraus, W. E. (2018). A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease. Nucleic Acids Research, 46(15), 7772-7792. https://doi.org/10.1093/nar/gky570

Genome-wide association studies (GWAS), relying on hundreds of thousands of individuals, have revealed >200 genomic loci linked to metabolic disease (MD). Loss of insulin sensitivity (IS) is a key component of MD and we hypothesized that discovery of... Read More about A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease.

Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis (2018)
Journal Article
Herrod, P. J., Doleman, B., Blackwell, J. E., O’Boyle, F., Williams, J. P., Lund, J. N., & Phillips, B. E. (in press). Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis. Journal of the American Society of Hypertension, 12(4), https://doi.org/10.1016/j.jash.2018.01.008

The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from st... Read More about Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis.