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All Outputs (144)

Taking a broader view of things: towards a transdisciplinary approach to cancer (2017)
Journal Article
Rauch, C., Blott, S., & Stewart, S. (2017). Taking a broader view of things: towards a transdisciplinary approach to cancer. https://doi.org/10.13133/2532-5876_2.10

Cancer is widely considered an abnormality that emerges from within the body and which must be destroyed and defeated. But we still do not know precisely how and why cancer starts, and while a ‘magic bullet’ cure has failed to materialise, those adop... Read More about Taking a broader view of things: towards a transdisciplinary approach to cancer.

The SEISICAT study: a pilot study assessing 1 efficacy and safety of spironolactone in cats with congestive heart failure secondary to cardiomyopathy (2017)
Journal Article
James, R., Guillot, E., Garelli-Paar, C., Huxley, J., Grassi, V., & Cobb, M. (2018). The SEISICAT study: a pilot study assessing 1 efficacy and safety of spironolactone in cats with congestive heart failure secondary to cardiomyopathy. Journal of Veterinary Cardiology, 20(1), https://doi.org/10.1016/j.jvc.2017.11.001

Introduction The pathophysiology of heart failure involves activation of several neurohormonal systems including the renin-angiotensin-aldosterone system. The mineralocorticoid receptor antagonist spironolactone has been shown to be beneficial in hu... Read More about The SEISICAT study: a pilot study assessing 1 efficacy and safety of spironolactone in cats with congestive heart failure secondary to cardiomyopathy.

Quantitative analysis of antimicrobial use on British dairy farms (2017)
Journal Article
Hyde, R. M., Remnant, J. G., Bradley, A. J., Breen, J. E., Hudson, C. D., Davies, P. L., …Green, M. J. (in press). Quantitative analysis of antimicrobial use on British dairy farms. Veterinary Record, 181(25), https://doi.org/10.1136/vr.104614

Antimicrobial resistance has been reported to represent a growing threat to both human and animal health, and concerns have been raised around levels of antimicrobial usage (AMU) within the livestock industry. To provide a benchmark for dairy cattle... Read More about Quantitative analysis of antimicrobial use on British dairy farms.

Is Your Extra X Chromosome Holding You Back? An Insight into Female Education and Academic Careers in STEMM (2017)
Book Chapter
Alibhai, A., Saigar, M. M., Harding, E., & Rutland, C. S. (2017). Is Your Extra X Chromosome Holding You Back? An Insight into Female Education and Academic Careers in STEMM. In New pedagogical challenges in the 21st century. InTech. https://doi.org/10.5772/intechopen.71898

This review discusses whether gender inequality still exists within medical, scientific and engineering academia, with regards to the career development of academic staff. In the 1970s it was suggested that women who are talented and educated with fa... Read More about Is Your Extra X Chromosome Holding You Back? An Insight into Female Education and Academic Careers in STEMM.

The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms (2017)
Journal Article
Bradley, A. J., Leach, K. A., Green, M. J., Gibbons, J., Ohnstad, I. C., Black, D. H., …Breen, J. E. (in press). The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms. International Journal of Food Microbiology, https://doi.org/10.1016/j.ijfoodmicro.2017.12.022

The introduction of bedding dairy cows on recycled manure solids (RMS) in the UK led to concern by competent authorities that there could be an increased, unacceptable risk to animal and human health. A cross-sectional study was designed to evaluate... Read More about The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms.

Ultrasonographic scoring system for superficial digital flexor tendon injuries in horses: intra- and inter-rater variability (2017)
Journal Article
Alzola Domingo, R., Riggs, C. M., Gardner, D. S., & Freeman, S. (2017). Ultrasonographic scoring system for superficial digital flexor tendon injuries in horses: intra- and inter-rater variability. Veterinary Record, 181(24), https://doi.org/10.1136/vr.104233

Superficial digital flexor tendon (SDFT) tendinopathy is an important musculoskeletal problem in horses. The study objective was to validate an ultrasonographic scoring system for SDFT injuries. Ultrasonographic images from 14 Thoroughbred racehorses... Read More about Ultrasonographic scoring system for superficial digital flexor tendon injuries in horses: intra- and inter-rater variability.

Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle (2017)
Journal Article
Dai, Y., Ivell, R., & Anand-Ivell, R. (2017). Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle. Frontiers in Physiology, 8, https://doi.org/10.3389/fphys.2017.01033

Insulin-like peptide 3 (INSL3) and its specific receptor RXFP2 are both expressed by theca interna cells of the growing antral follicle where they form an essential regulatory element in the production of the steroid precursor androstenedione. Using... Read More about Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle.

Expression profiles of genes involved in TLRs and NLRs signaling pathways of water buffaloes infected with Fasciola gigantica (2017)
Journal Article
Zhang, F., Hou, J., Guo, A., Tian, A., Shi, W., Sheng, Z., …Zhu, X. (2018). Expression profiles of genes involved in TLRs and NLRs signaling pathways of water buffaloes infected with Fasciola gigantica. Molecular Immunology, 94, https://doi.org/10.1016/j.molimm.2017.12.007

Infection of ruminants and humans with Fasciola gigantica is attracting increasing attention due to its economic impact and public health significance. However, little is known of innate immune responses during F. gigantica infection. Here, we invest... Read More about Expression profiles of genes involved in TLRs and NLRs signaling pathways of water buffaloes infected with Fasciola gigantica.

Dynamic expression of cytokine and transcription factor genes during experimental Fasciola gigantica infection in buffaloes (2017)
Journal Article
Shi, W., Wei, Z., Elsheikha, H. M., Zhang, F., Sheng, Z., Lu, K., …Zhu, X. (2017). Dynamic expression of cytokine and transcription factor genes during experimental Fasciola gigantica infection in buffaloes. Parasites and Vectors, 10(1), Article 602. https://doi.org/10.1186/s13071-017-2538-1

Background Determining the mechanisms involved in the immune-pathogenesis of the tropical liver fluke, Fasciola gigantica, is crucial to the development of any effective therapeutic intervention. Here, we examined the differential gene expression... Read More about Dynamic expression of cytokine and transcription factor genes during experimental Fasciola gigantica infection in buffaloes.

Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines (2017)
Journal Article
Davies, M., Alborough, R., Jones, L., Davis, C., Williams, C., & Gardner, D. S. (2017). Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines. Scientific Reports, 7(1), 1-9. https://doi.org/10.1038/s41598-017-17159-7

© 2017 The Author(s). Mineral content of complete pet food is regulated to ensure health of the companion animal population. Analysis of adherence to these regulatory guidelines has not been conducted. Here, mineral composition of complete wet (n = 9... Read More about Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines.

Analysing the opinions of UK veterinarians on practice-based research using corpus linguistic and mathematical methods (2017)
Journal Article
Huntley, S. J., Mahlberg, M., Wiegand, V., van Gennip, Y., Yang, H., Dean, R. S., & Brennan, M. L. (2018). Analysing the opinions of UK veterinarians on practice-based research using corpus linguistic and mathematical methods. Preventive Veterinary Medicine, 150, https://doi.org/10.1016/j.prevetmed.2017.11.020

The use of corpus linguistic techniques and other related mathematical analyses have rarely, if ever, been applied to qualitative data collected from the veterinary field. The aim of this study was to explore the use of a combination of corpus lingui... Read More about Analysing the opinions of UK veterinarians on practice-based research using corpus linguistic and mathematical methods.

Equine meniscal degeneration is associated with medial femorotibial osteoarthritis (2017)
Journal Article
Dubuc, J., Girard, C., Richard, H., De Lasalle, J., & Laverty, S. (2018). Equine meniscal degeneration is associated with medial femorotibial osteoarthritis. Equine Veterinary Journal, 50(1), 133-140. https://doi.org/10.1111/evj.12716

Background: There is limited information available concerning normal equine meniscal morphology, its degeneration and role in osteoarthritis (OA). Objectives: To characterise normal equine meniscal morphology and lesions and to explore the relation... Read More about Equine meniscal degeneration is associated with medial femorotibial osteoarthritis.

A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle (2017)
Journal Article
Meyer, A., Bond, K., Van Winden, S., Green, M. J., & Guitian, J. (2018). A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle. Preventive Veterinary Medicine, 150, 30-37. https://doi.org/10.1016/j.prevetmed.2017.11.016

Johne’s disease is a serious wasting disease of ruminants that is of high economic importance for the dairy sector in particular. The chronic nature of the disease, the fluctuations in antibody levels and the limited ability of diagnostic tests to id... Read More about A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle.

Post-temporary ligation intra-operative mesenteric portovenography: comparison with computed tomographic angiography for investigation of portosystemic shunts (2017)
Journal Article
Parry, A., & White, R. N. (2018). Post-temporary ligation intra-operative mesenteric portovenography: comparison with computed tomographic angiography for investigation of portosystemic shunts. Journal of Small Animal Practice, 59(2), 106-111. https://doi.org/10.1111/jsap.12786

Objectives: Comparison of pre-operative computed tomographic angiography and post-temporary full ligation intraoperative mesenteric portovenography for the documentation of the intrahepatic portal vasculature in patients with single extrahepatic port... Read More about Post-temporary ligation intra-operative mesenteric portovenography: comparison with computed tomographic angiography for investigation of portosystemic shunts.

Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal osteoarthritis (2017)
Journal Article
Corr, S. A., Gardner, D. S., Langley-Hobbs, S., Ness, M. G., Kitchener, A. C., & Sinclair, K. D. (2017). Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal osteoarthritis. Scientific Reports, 7, Article 15685. https://doi.org/10.1038/s41598-017-15902-8

Our recent report detailing the health status of cloned sheep concluded that the animals had aged normally. This is in stark contrast to reports on Dolly (first animal cloned from adult cells) whose diagnoses of osteoarthritis (OA) at 5½ years of age... Read More about Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal osteoarthritis.

Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging (2017)
Journal Article
Naemat, A., Sinjab, F., McDonald, A., Downes, A., Elfick, A., Elsheikha, H. M., & Notingher, I. (2018). Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging. Journal of Raman Spectroscopy, 49(3), 412-423. https://doi.org/10.1002/jrs.5296

Improved understanding of the mechanism of nutrient’s uptake can enable targeted manipulation of nutrient sensing pathways in medically important pathogens to a greater degree than is currently possible. In this context, we present the use of spontan... Read More about Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging.

The contribution of previous lameness events and body condition score to the occurrence of lameness in dairy herds: a study of 2 herds (2017)
Journal Article
Randall, L., Green, M., Green, L., Chagunda, M., Mason, C., Archer, S., & Huxley, J. (2018). The contribution of previous lameness events and body condition score to the occurrence of lameness in dairy herds: a study of 2 herds. Journal of Dairy Science, 101(2), https://doi.org/10.3168/jds.2017-13439

It has been demonstrated that low body condition and previous occurrence of lameness increase the risk of future lameness in dairy cows. To date the population attributable fraction (PAF), which provides an estimate of the contribution that a risk fa... Read More about The contribution of previous lameness events and body condition score to the occurrence of lameness in dairy herds: a study of 2 herds.

Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China (2017)
Journal Article
Bhandare, S. G., Warry, A., Emes, R. D., Su, J., Barrow, P. A., & Atterbury, R. J. (2017). Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China. Genome Announcements, 5(47), Article e01019-17. https://doi.org/10.1128/genomeA.01019-17

The complete genome sequences of seven closely related Vibrio cholerae phages isolated from environmental sites in southeastern China are reported here. Phages QH, CJY, H1, H2, H3, J2, and J3 are members of the Podoviridae family and are highly simil... Read More about Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China.

Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature (2017)
Journal Article
Robinson, N. J., Lyons, E., Grindlay, D., & Brennan, M. L. (in press). Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature. Veterinary Sciences, 4(4), https://doi.org/10.3390/vetsci4040058

Rabbits and guinea pigs are increasingly popular pets in the UK, yet little is known about their common ailments, or how these relate to what appears in the published literature. The aim of this study was to characterise the common conditions of rabb... Read More about Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature.