All Outputs (2)

A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid (2017)
Journal Article
Andrews, K. G., Faizova, R., & Denton, R. M. (in press). A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid. Nature Communications, 8, Article 15913. https://doi.org/10.1038/ncomms15913

Amines are a fundamentally important class of biologically active compounds and the ability to manipulate their physicochemical properties through the introduction of fluorine is of paramount importance in medicinal chemistry. Current synthesis metho... Read More about A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid.

A more critical role for silicon in the catalytic Staudinger amidation: silanes as non-innocent reductants (2017)
Journal Article
Andrews, K. G., & Denton, R. M. (2017). A more critical role for silicon in the catalytic Staudinger amidation: silanes as non-innocent reductants. Chemical Communications, 53(57), 7982-7985. https://doi.org/10.1039/C7CC03076B