All Outputs (5)

Glycaemic, gastrointestinal and appetite responses to breakfast porridges from ancient cereal grains: a MRI pilot study in healthy humans (2017)
Journal Article
Alyami, J., Ladd, N., Pritchard, S. E., Hoad, C. L., Abdul Sultan, A., Spiller, R. C., …Taylor, M. A. (2017). Glycaemic, gastrointestinal and appetite responses to breakfast porridges from ancient cereal grains: a MRI pilot study in healthy humans. Food Research International, https://doi.org/10.1016/j.foodres.2017.11.071

Cereal grain based porridges are commonly consumed throughout the world. Whilst some data are available for varieties that are popular in the Western world such as oats and rye, other ‘ancient’ grains used in the East and in Africa such as millets ar... Read More about Glycaemic, gastrointestinal and appetite responses to breakfast porridges from ancient cereal grains: a MRI pilot study in healthy humans.

MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans (2017)
Journal Article
Khalaf, A., Hoad, C., Menys, A., Nowak, A., Taylor, S. A., Paparo, S., …Moran, G. W. (2018). MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans. Neurogastroenterology and Motility, 30(1), Article e13182. https://doi.org/10.1111/nmo.13182

Background: Feeding triggers inter-related gastrointestinal (GI) motor, peptide and appetite responses. These are rarely studied together due to methodological limitations. Recent MRI advances allow pan-intestinal, non-invasive assessment of motility... Read More about MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans.

Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans (2017)
Journal Article
Murray, K., Hoad, C. L., Mudie, D. M., Wright, J., Heissam, K., Abrehart, N., …Marciani, L. (2017). Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans. Molecular Pharmaceutics, 14(8), 2629-2638. https://doi.org/10.1021/acs.molpharmaceut.7b00095

The rate and extent of drug dissolution and absorption from solid oral dosage forms is highly dependent on the volume of liquid in the gastrointestinal tract (GIT). However, little is known about the time course of GIT liquid volumes after drinking a... Read More about Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans.

Randomised clinical trial: mesalazine versus placebo in the prevention of diverticulitis recurrence (2017)
Journal Article
Kruis, W., Kardalinos, V., Eisenbach, T., Lukas, M., Vich, T., Bunganic, I., …Spiller, R. (2017). Randomised clinical trial: mesalazine versus placebo in the prevention of diverticulitis recurrence. Alimentary Pharmacology and Therapeutics, 46(3), 282-291. https://doi.org/10.1111/apt.14152

Background Previous studies have reached conflicting conclusions regarding the efficacy of mesalazine in the prevention of recurrent diverticulitis. Aim To investigate the efficacy and safety of mesalazine granules in the prevention of recur... Read More about Randomised clinical trial: mesalazine versus placebo in the prevention of diverticulitis recurrence.

Assessment of motion of colonic contents in the human colon using MRI tagging (2017)
Journal Article
Pritchard, S. E., Paul, J., Major, G., Marciani, L., Gowland, P. A., Spiller, R. C., & Hoad, C. (2017). Assessment of motion of colonic contents in the human colon using MRI tagging. Neurogastroenterology and Motility, 29(9), Article e13091. https://doi.org/10.1111/nmo.13091

Background We have previously reported a non-invasive, semi-automated technique to assess motility of the wall of the ascending colon (AC) using Magnetic Resonance Imaging. This study investigated the feasibility of using a tagged MRI technique to vi... Read More about Assessment of motion of colonic contents in the human colon using MRI tagging.