All Outputs (9)

Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis (2017)
Journal Article
Khan, U. T., Walker, A. J., Baig, S., Card, T. R., Kirwan, C. C., & Grainge, M. J. (2017). Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis. BMC Cancer, 17(747), https://doi.org/10.1186/s12885-017-3719-1

Background Breast cancer patients are at an increased risk of venous thromboembolism (VTE). However, current evidence as to whether VTE increases the risk of mortality in breast cancer patients is conflicting. We present data from a large cohort of... Read More about Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis.

Investigating the mechanisms of endometrial cancer risk in polycystic ovary syndrome: can UK biobank help? (2017)
Journal Article
Atiomo, W., Lakshmi Karanam, V., Sian, M., & Grainge, M. (2017). Investigating the mechanisms of endometrial cancer risk in polycystic ovary syndrome: can UK biobank help?. Obstetrics & gynecology international journal, 8(1), Article 00277. https://doi.org/10.15406/ogij.2017.08.00277

Background: UK biobank was set up to investigate the respective contributions of genetic predisposition and environmental exposure to the development of disease and recruited participants between 2006 and 2010. Our aim was to investigate the feasibil... Read More about Investigating the mechanisms of endometrial cancer risk in polycystic ovary syndrome: can UK biobank help?.

Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study (2017)
Journal Article
Pearce, F. A., Hubbard, R., Grainge, M. J., Watts, R. A., Abhishek, A., & Lanyon, P. C. (in press). Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study. QJM: An International Journal of Medicine, https://doi.org/10.1093/qjmed/hcx194

Background: People with granulomatosis with polyangiitis (GPA) commonly describe long delays before diagnosis. Aim: To study the natural history of GPA prior to diagnosis using primary care data, and determine whether clinical features could be iden... Read More about Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study.

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis (2017)
Journal Article
Osinubi, O., Grainge, M. J., Ahmed, A., Batchelor, J. M., Grindlay, D., Thompson, A., & Ratib, S. (2018). The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 178(4), 863-878. https://doi.org/10.1111/bjd.16049

Background: Vitiligo is a chronic disorder causing skin depigmentation with global prevalence varying from 0.2 to 1.8%. UK guidelines recommend assessment of psychological state during clinical evaluation of vitiligo. However, the prevalence of psych... Read More about The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis.

Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom (2017)
Journal Article
Betts, G., Ratschen, E., Opazo-Breton, M., & Grainge, M. J. (2018). Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom. Journal of Public Health, 40(3), 540–548. https://doi.org/10.1093/pubmed/fdx123

Background: Recent guidelines from the United Kingdom recommend that men and women should drink no more than 14 units of alcohol per week. This recommendation takes into account the link between alcohol and several cancers; however, there is a dearth... Read More about Alcohol consumption and risk of common cancers: evidence from a cohort of adults from the United Kingdom.

Drugs for discoid lupus erythematosus (2017)
Journal Article
Jessop, S., Whitelaw, D. A., Grainge, M. J., & Jayasekera, P. (in press). Drugs for discoid lupus erythematosus. Cochrane Database of Systematic Reviews, 5, Article CD002954. https://doi.org/10.1002/14651858.CD002954.pub3

BACKGROUND: Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus, which can cause scarring. Many drugs have been used to treat this disease and some (such as thalidomide, cyclophosphamide and azathioprine) are potentially toxic. Thi... Read More about Drugs for discoid lupus erythematosus.

Familial aggregation of rheumatoid arthritis and co-aggregation of autoimmune diseases in affected families: a nationwide population-based study (2017)
Journal Article
Kuo, C. F., Grainge, M. J., Valdes, A. M., See, L. C., Yu, K. H., Steven Shaw, S. W., …Doherty, M. (2017). Familial aggregation of rheumatoid arthritis and co-aggregation of autoimmune diseases in affected families: a nationwide population-based study. Rheumatology, 56(6), 928-933. https://doi.org/10.1093/rheumatology/kew500

© The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. Objective. The aim was to estimate familial relative risk (RR) for RA and other autoimmune diseases and the genetic contri... Read More about Familial aggregation of rheumatoid arthritis and co-aggregation of autoimmune diseases in affected families: a nationwide population-based study.

Recurrence risk of venous thromboembolism and hormone use in women from England: a cohort study using clinical practice research datalink (2017)
Journal Article
Kiconco, S., Abdul Sultan, A., & Grainge, M. J. (2017). Recurrence risk of venous thromboembolism and hormone use in women from England: a cohort study using clinical practice research datalink. British Journal of Haematology, 177(1), 127-135. https://doi.org/10.1111/bjh.14516

It is vital to identify people with low recurrence risk of venous thromboembolism (VTE) so as to protect them from dangers of prolonged anticoagulation therapy. Among women who develop VTE following hormone use, the evidence as to whether their risk... Read More about Recurrence risk of venous thromboembolism and hormone use in women from England: a cohort study using clinical practice research datalink.

Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study (2017)
Journal Article
Abhishek, A., Doherty, M., Kuo, C., Mallen, C. D., Zhang, W., & Grainge, M. J. (2017). Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study. Rheumatology, 56(5), 736-744. https://doi.org/10.1093/rheumatology/kew468

Objectives: The objectives of this study were to examine changes in incidence and prevalence of RA between 1990 and 2014, and to explore if there is any geographic variation in incidence and prevalence of RA in the UK Methods: Design Prospective... Read More about Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study.