All Outputs (2)

Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation (2017)
Journal Article
Hamad, B. K., Pathak, M., Manna, R., Fischer, P. M., Emsley, J., & Dekker, L. V. (2017). Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation. Journal of Thrombosis and Haemostasis, 15(9), 1818-1828. https://doi.org/10.1111/jth.13773

Background: Corn trypsin inhibitor (CTI) has selectivity for serine proteases coagulation factor XII (FXII) and trypsin. CTI is in widespread use as a reagent that specifically inhibits the intrinsic pathway of blood coagulation but not the extrinsic... Read More about Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation.

Concise review: Emerging Drugs Targeting Epithelial Cancer Stem-like Cells (2017)
Journal Article
Ahmed, M., Chaudhari, K., Babaei?Jadidi, R., Dekker, L. V., & Shams Nateri, A. (2017). Concise review: Emerging Drugs Targeting Epithelial Cancer Stem-like Cells. STEM CELLS, 35(4), 839-850. https://doi.org/10.1002/stem.2579

Increasing evidence suggests that cancer cell populations contain a small proportion of cells that display stem?like cell properties and which may be responsible for overall tumor maintenance. These cancer stem?like cells (CSCs) appear to have unique... Read More about Concise review: Emerging Drugs Targeting Epithelial Cancer Stem-like Cells.