Middle East respiratory syndrome

Arabi, Yaseen M.; Balkhy, Hanan H.; Hayden, Frederick G.; Bouchama, Abderrezak; Luke, Thomas; Baillie, J. Kenneth; Al-Omari, Awad; Hajeer, Ali H.; Senga, Mikiko; Denison, Mark R.; Nguyen-Van-Tam, Jonathan S.; Shindo, Nahoko; Bermingham, Alison; Chappell, James D.; Van Kerkhove, Maria D.; Fowler, Robert A.

doi:10.1056/NEJMsr1408795

All Outputs (9)

Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study (2017)
Journal Article
Fragaszy, E. B., Warren-Gash, C., White, P. J., Zambon, M., Edmunds, W. J., Nguyen-Van-Tam, J. S., & Hayward, A. C. (2018). Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study. Influenza and Other Respiratory Viruses, 12(1), 171-182. https://doi.org/10.1111/irv.12506

Background: Estimates of health?related quality of life (HRQoL) and work/school absences for influenza are typically based on medically attended cases or those meeting influenza?like?illness (ILI) case definitions and thus biased towards severe disea... Read More about Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study.

Antiviral Treatment for Pandemic Influenza: Conceptualisation of a Coupled Behavioural and Epidemic Agent-Based Simulation Model (2017)
Conference Proceeding
Venkatesan, S., Siebers, P., & Nguyen-Van-Tam, J. (2017). Antiviral Treatment for Pandemic Influenza: Conceptualisation of a Coupled Behavioural and Epidemic Agent-Based Simulation Model

Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe (2017)
Journal Article
Alimi, Y., Lim, W., Lansbury, L. E., Leonardi-Bee, J., & Nguyen-Van-Tam, J. S. (2017). Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe. Journal of Clinical Virology, 95, https://doi.org/10.1016/j.jcv.2017.07.019

Community-acquired pneumonia (CAP) is an important respiratory disease and the fifth leading cause of mortality in Europe. The development of molecular diagnostic tests has highlighted the contributions of respiratory viruses to the aetiology of CAP,... Read More about Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe.

Influenza in long-term care facilities (2017)
Journal Article
Lansbury, L. E., Brown, C. S., & Nguyen-Van-Tam, J. S. (2017). Influenza in long-term care facilities. Influenza and Other Respiratory Viruses, 11(5), 356-366. https://doi.org/10.1111/irv.12464

Long-term care facility environments and the vulnerability of their residents provide a setting conducive to the rapid spread of influenza virus and other respiratory pathogens. Infections may be introduced by staff, visitors or new or transferred re... Read More about Influenza in long-term care facilities.

Evidence synthesis and decision modelling to support complex decisions: stockpiling neuraminidase inhibitors for pandemic influenza usage (2017)
Journal Article
Watson, S. I., Chen, Y., Nguyen-Van-Tam, J. S., Myles, P. R., Venkatesan, S., Zambon, M., …Lilford, R. J. (2017). Evidence synthesis and decision modelling to support complex decisions: stockpiling neuraminidase inhibitors for pandemic influenza usage. F1000Research, 5, Article 2293. https://doi.org/10.12688/f1000research.9414.2

Objectives: The stockpiling of neuraminidase inhibitor (NAI) antivirals as a defence against pandemic influenza is a significant public health policy decision that must be made despite a lack of conclusive evidence from randomised controlled trials r... Read More about Evidence synthesis and decision modelling to support complex decisions: stockpiling neuraminidase inhibitors for pandemic influenza usage.

Effectiveness of 2009 pandemic influenza A(H1N1) vaccines: a systematic review and meta-analysis (2017)
Journal Article
Lansbury, L. E., Smith, S., Beyer, W., Karamehic, E., Pasic-Juhas, E., Sikira, H., …Nguyen-Van-Tam, J. (in press). Effectiveness of 2009 pandemic influenza A(H1N1) vaccines: a systematic review and meta-analysis. Vaccine, https://doi.org/10.1016/j.vaccine.2017.02.059

Background: The clinical effectiveness of monovalent influenza A(H1N1)pdm09 vaccines has not been comprehensively summarised. We undertook a systematic review and meta-analysis to assess vaccine effectiveness (VE) for adjuvanted and unadjuvanted vacc... Read More about Effectiveness of 2009 pandemic influenza A(H1N1) vaccines: a systematic review and meta-analysis.

Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an Individual Participant Data (IPD) meta-analysis (2017)
Journal Article
Venkatesan, S., Myles, P. R., Leonardi-Bee, J., Muthuri, S. G., Al Masri, M., Andrews, N., …Nguyen-Van-Tam, J. S. (2017). Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an Individual Participant Data (IPD) meta-analysis. Clinical Infectious Diseases, 64(10), 1328-1334. https://doi.org/10.1093/cid/cix127

Background: While evidence exists to support the effectiveness of neuraminidase inhibitors (NAIs) in reducing mortality when given to hospitalized patients with A(H1N1)pdm09 virus infection, the impact of outpatient treatment on hospitalization has n... Read More about Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an Individual Participant Data (IPD) meta-analysis.

Middle East respiratory syndrome (2017)
Journal Article
Arabi, Y. M., Balkhy, H. H., Hayden, F. G., Bouchama, A., Luke, T., Baillie, J. K., …Fowler, R. A. (2017). Middle East respiratory syndrome. New England Journal of Medicine, 376(6), 584-594. https://doi.org/10.1056/NEJMsr1408795

The Middle East respiratory syndrome is caused by a coronavirus that was first identified in Saudi Arabia in 2012. Periodic outbreaks continue to occur in the Middle East and elsewhere. This report provides the latest information on MERS.