All Outputs (3)

Reply to ‘The population genetics of pangenomes’ (2017)
Journal Article
McInerney, J. O., McNally, A., & O'Connell, M. J. (2017). Reply to ‘The population genetics of pangenomes’. Nature Microbiology, 2(12), Article 1575. https://doi.org/10.1038/s41564-017-0068-4

Function-related replacement of bacterial siderophore pathways (2017)
Journal Article
Moore, B. S., Jensen, P. R., Letzel, A., Crüsemann, M., Bruns, H., Crusemann, M., …Ziemert, N. (2018). Function-related replacement of bacterial siderophore pathways. ISME Journal, 12(2), 320-329. https://doi.org/10.1038/ismej.2017.137

© The Author(s) 2018. Bacterial genomes are rife with orphan biosynthetic gene clusters (BGCs) associated with secondary metabolism of unrealized natural product molecules. Often up to a tenth of the genome is predicted to code for the biosynthesis o... Read More about Function-related replacement of bacterial siderophore pathways.

Why prokaryotes have pangenomes (2017)
Journal Article
McInerney, J. O., McNally, A., & O'Connell, M. J. (2017). Why prokaryotes have pangenomes. Nature Microbiology, 2(4), https://doi.org/10.1038/nmicrobiol.2017.40

The existence of large amounts of within-species genome content variability is puzzling. Population genetics tells us that fitness effects of new variants—either deleterious, neutral or advantageous—combined with the long-term effective population si... Read More about Why prokaryotes have pangenomes.