All Outputs (5)

Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging (2017)
Journal Article
Naemat, A., Sinjab, F., McDonald, A., Downes, A., Elfick, A., Elsheikha, H. M., & Notingher, I. (2018). Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging. Journal of Raman Spectroscopy, 49(3), 412-423. https://doi.org/10.1002/jrs.5296

Improved understanding of the mechanism of nutrient’s uptake can enable targeted manipulation of nutrient sensing pathways in medically important pathogens to a greater degree than is currently possible. In this context, we present the use of spontan... Read More about Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging.

Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery (2017)
Journal Article
Boitor, R., Kong, K., Shipp, D., Varma, S., Koloydenko, A., Kusum, K., …Ioan, N. (in press). Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery. Biomedical Optics Express, 8(12), https://doi.org/10.1364/BOE.8.005749

Multimodal spectral histopathology (MSH), an optical technique combining tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), was previously proposed for detection of residual basal cell carcinoma (BCC) at the surface of surgical... Read More about Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery.

Label-free Raman hyperspectral imaging of single cells cultured on polymer substrates (2017)
Journal Article
Sinjab, F., Sicilia, G., Shipp, D., Marlow, M., & Notingher, I. (2017). Label-free Raman hyperspectral imaging of single cells cultured on polymer substrates. Applied Spectroscopy, 71(12), https://doi.org/10.1177/0003702817715042

While Raman hyper-spectral imaging has been widely used for label-free mapping of biomolecules in cells, these measurements require the cells to be cultured on weakly Raman scattering substrates. However, many applications in biological sciences and... Read More about Label-free Raman hyperspectral imaging of single cells cultured on polymer substrates.

Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization (2017)
Journal Article
Mazza, G., Al-Akkad, W., Telese, A., Longato, L., Urbani, L., Robinson, B., …Pinzani, M. (in press). Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization. Scientific Reports, 7, Article 5534. https://doi.org/10.1038/s41598-017-05134-1

The development of human liver scaffolds retaining their 3-dimensional structure and extra-cellular matrix (ECM) composition is essential for the advancement of liver tissue engineering. We report the design and validation of a new methodology for th... Read More about Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization.

Raman spectroscopy: techniques and applications in the life sciences (2017)
Journal Article
Shipp, D., Sinjab, F., & Notingher, I. (2017). Raman spectroscopy: techniques and applications in the life sciences. Advances in Optics and Photonics, 9(2), 315-428. https://doi.org/10.1364/AOP.9.000315

Raman spectroscopy is an increasingly popular technique in many areas including biology and medicine. It is based on Raman scattering, a phenomenon in which incident photons lose or gain energy via interactions with vibrating molecules in a sample. T... Read More about Raman spectroscopy: techniques and applications in the life sciences.