Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene

Warner, Sophie C.; van Meurs, Joyce B.J.; Schiphof, Dieuwke; Bierma-Zeinstra, Sita M.; Hofman, Albert; Uitterlinden, Andre G.; Richardson, Helen; Jenkins, Wendy; Doherty, Michael; Valdes, Ana M.

doi:10.1038/ejhg.2016.196

All Outputs (2)

Knee pain and related health in the community study (KPIC): a cohort study protocol (2017)
Journal Article
Fernandes, G. S., Sarmanova, A., Warner, S. C., Harvey, H., Akin-Akinyosoye, K., Richardson, H., …Doherty, M. (in press). Knee pain and related health in the community study (KPIC): a cohort study protocol. BMC Musculoskeletal Disorders, 18(404), https://doi.org/10.1186/s12891-017-1761-4

Background: The incidence, progression and related risk factors for recent-onset knee pain (KP) remain uncertain. This study aims to examine the natural history of KP including incidence and progression and to identify possible phenotypes and their a... Read More about Knee pain and related health in the community study (KPIC): a cohort study protocol.

Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene (2017)
Journal Article
Warner, S. C., van Meurs, J. B., Schiphof, D., Bierma-Zeinstra, S. M., Hofman, A., Uitterlinden, A. G., …Valdes, A. M. (in press). Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene. European Journal of Human Genetics, https://doi.org/10.1038/ejhg.2016.196

Neuropathic pain-like joint symptoms (NP) are seen in a proportion of individuals diagnosed with osteoarthritis (OA) and post total joint replacement (TJR). In this study, we performed a genome-wide association study (GWAS) using NP as defined by the... Read More about Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene.