All Outputs (2)

A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study (2017)
Journal Article
Crossland, H., Smith, K., Atherton, P. J., & Wilkinson, D. J. (2017). A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study. Biochemical and Biophysical Research Communications, 494(3-4), https://doi.org/10.1016/j.bbrc.2017.10.085

The precise roles that the major proteolytic pathways play in the regulation of skeletal muscle mass remain incompletely understood, in part due to technical limitations associated with current techniques used to quantify muscle protein breakdown (MP... Read More about A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study.

Peroxisome proliferator-activated receptor ? agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats (2017)
Journal Article
Crossland, H., Constantin-Teodosiu, D., Gardiner, S. M., & Greenhaff, P. (2017). Peroxisome proliferator-activated receptor ? agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats. Clinical Science, 131(13), 1437-1447. https://doi.org/10.1042/CS20170958

The peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (Rosi) appears to provide protection against organ dysfunction during endotoxaemia. We examined the potential benefits of Rosi on skeletal muscle protein maintenance and c... Read More about Peroxisome proliferator-activated receptor ? agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats.