Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
(2017)
Journal Article
Mwenechanya, R., Kovarova, J., Dickens, N. J., Mudaliar, M., Herzyk, P., Vicent, I. M., …Barrett, M. P. (2017). Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), Article e0005649. https://doi.org/10.1371/journal.pntd.0005649
Amphotericin B has emerged as the therapy of choice for use against the leishmaniases. Administration of the drug in its liposomal formulation as a single injection is being promoted in a campaign to bring the leishmaniases under control. Understandi... Read More about Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.