All Outputs (2)

Altered glutamine metabolism in breast cancer: subtype dependencies and alternative adaptations (2017)
Journal Article
El Ansari, R., McIntyre, A., Craze, M. L., Ellis, I. O., Rakha, E. A., & Green, A. R. (in press). Altered glutamine metabolism in breast cancer: subtype dependencies and alternative adaptations. Histopathology, https://doi.org/10.1111/his.13334

Cancer cells must alter their metabolism in order to satisfy the demands of necessary energy and cellular building blocks. These metabolic alterations are mediated by many oncogenic changes that affect cellular signalling pathways, which result in su... Read More about Altered glutamine metabolism in breast cancer: subtype dependencies and alternative adaptations.

MicroRNA regulation of glycolytic metabolism in glioblastoma multiforme (2017)
Journal Article
Alfardus, H., McIntyre, A., & Smith, S. J. (2017). MicroRNA regulation of glycolytic metabolism in glioblastoma multiforme. BioMed Research International, 2017, https://doi.org/10.1155/2017/9157370

Glioblastoma multiforme (GBM) is the most aggressive and common malignant brain and central nervous system tumour. A well-known hallmark of GMB, and many other tumours, is aerobic glycolysis. microRNAs (miRNAs) are a class of short non-protein coding... Read More about MicroRNA regulation of glycolytic metabolism in glioblastoma multiforme.