All Outputs (90)

The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink (2016)
Journal Article
Pearce, F. A., Grainge, M. J., Lanyon, P. C., Watts, R. A., & Hubbard, R. B. (in press). The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink. Rheumatology, https://doi.org/10.1093/rheumatology/kew413

Objectives: To estimate the incidence, prevalence and mortality of Granulomatosis with polyangiitis (GPA) in the United Kingdom. Methods: We conducted a historical cohort study using data from the Clinical Practice Research Datalink and Hospital Epi... Read More about The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink.

Meta-analysis of operative experiences of general surgery trainees during training (2016)
Journal Article
Elsey, E., Griffiths, G., Humes, D., & West, J. (in press). Meta-analysis of operative experiences of general surgery trainees during training. British Journal of Surgery, 104(1), https://doi.org/10.1002/bjs.10396

BACKGROUND: General surgical training curricula around the world set defined operative numbers to be achieved before completion of training. However, there are few studies reporting total operative experience in training. This systematic review aimed... Read More about Meta-analysis of operative experiences of general surgery trainees during training.

Adverse events after first, single, mesh and non-mesh surgical procedures for stress urinary incontinence and pelvic organ prolapse in Scotland, 1997–2016: a population-based cohort study (2016)
Journal Article
Morling, J. R., McAllister, D. A., Agur, W., Fischbacher, C. M., Glazener, C. M., Guerrero, K., …Wood, R. (2017). Adverse events after first, single, mesh and non-mesh surgical procedures for stress urinary incontinence and pelvic organ prolapse in Scotland, 1997–2016: a population-based cohort study. Lancet, 389(10069), 629-640. https://doi.org/10.1016/S0140-6736%2816%2932572-7

Background Concerns have been raised about the safety of surgery for stress urinary incontinence and pelvic organ prolapse using transvaginal mesh. We assessed adverse outcomes after first, single mesh procedures and comparable non-mesh procedures... Read More about Adverse events after first, single, mesh and non-mesh surgical procedures for stress urinary incontinence and pelvic organ prolapse in Scotland, 1997–2016: a population-based cohort study.

Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study (2016)
Journal Article
Sultan, A. A., West, J., Grainge, M. J., Riley, R. D., Tata, L. J., Stephansson, O., …Ludvigsson, J. F. (2016). Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ, 355(i6253), https://doi.org/10.1136/bmj.i6253

Objective: To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum). Design: Cohort study. Setting: Records from England based Clinical Practice Research Datalink (CPRD)... Read More about Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study.

English stop-smoking services: one-year outcomes (2016)
Journal Article
Bauld, L., Hiscock, R., Dobbie, F., Aveyard, P., Coleman, T., Leonardi-Bee, J., …McEwan, A. (2016). English stop-smoking services: one-year outcomes. International Journal of Environmental Research and Public Health, 13(12), Article 1175. https://doi.org/10.3390/ijerph13121175

The UK is a global leader in stop-smoking support—providing free behavioral support and cessation medication via stop smoking services (SSS) without charge to smokers. This study aimed to explore the client and service characteristics associated with... Read More about English stop-smoking services: one-year outcomes.

Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families (2016)
Journal Article
Chou, I., Kuo, C., Huang, Y., Grainge, M. J., Valdes, A. M., See, L., …Doherty, M. (in press). Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families. Schizophrenia Bulletin, https://doi.org/10.1093/schbul/sbw159

Strong familial aggregation of schizophrenia has been reported but there is uncertainty concerning the degree of genetic contribution to the phenotypic variance of the disease. This study aimed to examine the familial aggregation and heritability of... Read More about Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families.

The association of low birth weight with serum C reactive protein in three year old children living in Cuba: a population-based prospective study (2016)
Journal Article
Venero-Fernández, S. J., Fundora-Hernández, H., Batista-Gutierrez, L., Suárez-Medina, R., de la C. Mora-Faife, E., del Valle-Infante, I., …Fogarty, A. W. (in press). The association of low birth weight with serum C reactive protein in three year old children living in Cuba: a population-based prospective study. American Journal of Human Biology, https://doi.org/10.1002/ajhb.22936

Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study (2016)
Journal Article
Othman, F., Crooks, C. J., & Card, T. R. (2016). Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study. BMJ, 355, Article i5813. https://doi.org/10.1136/bmj.i5813

Objective To examine the risk of community acquired pneumonia before and after prescription of proton pump inhibitor (PPI) and assess whether unmeasured confounding explains this association. Design Cohort study and self controlled case series. S... Read More about Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study.

Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease (2016)
Journal Article
Skelly, R., Brown, L., & Fogarty, A. W. (2017). Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease. Parkinsonism and Related Disorders, 35, https://doi.org/10.1016/j.parkreldis.2016.11.004

Background: Punctual delivery of dopaminergic medication to Parkinson's disease (PD) patients may be important in optimizing disease control. We tested the hypothesis that prompt delivery of l-dopa medications to emergency hospital inpatients was ass... Read More about Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease.

The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study (2016)
Journal Article
Chu, T. P., Moran, G. W., & Card, T. R. (2016). The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study. Journal of Crohn's and Colitis, 11(5), 578-585. https://doi.org/10.1093/ecco-jcc/jjw192

Background and Aims: Numerous studies have established that mortality risk in IBD patients is higher than the general population, but the causes of death have seldom been examined. We aimed to describe causes of death in IBD. Methods: A matched co... Read More about The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study.

The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England (2016)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2016). The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England. PLoS ONE, 11(10), 1-16. https://doi.org/10.1371/journal.pone.0165507

Background: We have assessed whether the linkage between routine primary and secondary care records provided an opportunity to develop an improved population based co-morbidity score with the combined information on co-morbidities from both health ca... Read More about The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study (2016)
Journal Article
Barr, H. L., Halliday, N., Barrett, D. A., Williams, P., Forrester, D. L., Peckham, D., …Fogarty, A. W. (2017). Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16(2), 230-238. https://doi.org/10.1016/j.jcf.2016.10.005

Background Pulmonary P. aeruginosa infection is associated with poor outcomes in cystic fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to expectorate sputum. Specific P. aeruginosa 2-alkyl-4-quinolones are det... Read More about Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study.

Involving private healthcare practitioners in an urban NCD sentinel surveillance system: lessons learned from Pune, India (2016)
Journal Article
Kroll, M., Phalkey, R., Dutta, S., Shukla, S., Butsch, C., Bharucha, E., & Kraas, F. (2016). Involving private healthcare practitioners in an urban NCD sentinel surveillance system: lessons learned from Pune, India. Global Health Action, 9(32635), 1-10. https://doi.org/10.3402/gha.v9.32635

Background: Despite the rising impact of non-communicable diseases (NCDs) on public health in India, lack of quality data and routine surveillance hampers the planning process for NCD prevention and control. Current surveillance programs focus largel... Read More about Involving private healthcare practitioners in an urban NCD sentinel surveillance system: lessons learned from Pune, India.

FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations (2016)
Journal Article
Skeggs, A., McKeever, T. M., Duley, L., Mitchell, E., Bradshaw, L., Mortimer, K., …Haydock, R. (2016). FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations. Trials, 17, https://doi.org/10.1186/s13063-016-1608-6

BACKGROUND: Asthma is one of the commonest chronic diseases in the UK. Acute exacerbations of asthma are unpredictable, disruptive and frightening. They cause considerable morbidity and account for a large component of the health service costs of ast... Read More about FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations.

NUTRItion and CLIMate (NUTRICLIM): investigating the relationship between climate variables and childhood malnutrition through agriculture, an exploratory study in Burkina Faso (2016)
Journal Article
Sorgho, R., Franke, J., Simboro, S., Phalkey, R., & Saeurborn, R. (in press). NUTRItion and CLIMate (NUTRICLIM): investigating the relationship between climate variables and childhood malnutrition through agriculture, an exploratory study in Burkina Faso. Public Health Reviews, 37(16), https://doi.org/10.1186/s40985-016-0031-6

Malnutrition remains a leading cause of death in children in low- and middle-income countries; this will be aggravated by climate change. Annually, 6.9 million deaths of children under 5 were attributable directly or indirectly to malnutrition. Altho... Read More about NUTRItion and CLIMate (NUTRICLIM): investigating the relationship between climate variables and childhood malnutrition through agriculture, an exploratory study in Burkina Faso.

Knowledge, attitude, and practices with respect to disease surveillance among urban private practitioners in Pune, India (2016)
Journal Article
Phalkey, R. K., Kroll, M., Dutta, S., Shukla, S., Butsch, C., Bharucha, E., & Kraas, F. (2016). Knowledge, attitude, and practices with respect to disease surveillance among urban private practitioners in Pune, India. Global Health Action, 8(28413), https://doi.org/10.3402/gha.v8.28413

BACKGROUND: Participation of private practitioners in routine disease surveillance in India is minimal despite the fact that they account for over 70% of the primary healthcare provision. We aimed to investigate the knowledge, attitudes, and practice... Read More about Knowledge, attitude, and practices with respect to disease surveillance among urban private practitioners in Pune, India.

Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India (2016)
Journal Article
Ahankari, A. S., Dixit, J., Fogarty, A. W., Tata, L. J., & Myles, P. R. (2016). Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India. BMJ Innovations, 2, https://doi.org/10.1136/bmjinnov-2016-000139

Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting. Methods: Participants included girls aged between 13... Read More about Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India.

Portrayal of tobacco smoking in popular women's magazines: a content analysis (2016)
Journal Article
Kasujee, N., Britton, J., Cranwell, J., Lyons, A., & Bains, M. (in press). Portrayal of tobacco smoking in popular women's magazines: a content analysis. Journal of Public Health, https://doi.org/10.1093/pubmed/fdw104

Background: Whilst many countries have introduced legislation prohibiting tobacco advertising and sponsorship, references to tobacco continue to appear in the media. This study quantified and characterized tobacco smoking content in popular women's m... Read More about Portrayal of tobacco smoking in popular women's magazines: a content analysis.

Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008 (2016)
Journal Article
Hutchinson, J. P., McKeever, T. M., Fogarty, A. W., Navaratnam, V., & Hubbard, R. B. (in press). Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008. European Respiratory Journal, 48, https://doi.org/10.1183/13993003.00378-2016

Introduction: International guidelines and new targeted therapies for idiopathic pulmonary fibrosis have increased the need for accurate diagnosis of interstitial lung disease, which may lead to more surgical lung biopsies. This study aims to assess... Read More about Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008.

Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2016)
Journal Article
Ierodiakonou, D., Garcia-Larsen, V., Logan, A., Groome, A., Cunha, S., Chivinge, J., …Boyle, R. J. (2016). Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis. Journal of the American Medical Association, 316(11), 1181-1192. https://doi.org/10.1001/jama.2016.12623

Importance: Timing of introduction of allergenic foods to the infant diet may influence the risk of allergic or autoimmune disease, but the evidence for this has not been comprehensively synthesized. Objective: To systematically review and meta-a... Read More about Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis.