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Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes (2016)
Journal Article
Tarale, P., Sivanesan, S., Daiwile, A. P., Stöger, R., Bafana, A., Naoghare, P. K., …Kannan, K. (2017). Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes. Archives of Toxicology, 91(7), 2629-2641. https://doi.org/10.1007/s00204-016-1899-0

Manganese (Mn) is an essential trace element required for optimal functioning of cellular biochemical pathways in the central nervous system. Elevated exposure to Mn through environmental and occupational exposure can cause neurotoxic effects resulti... Read More about Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes.