All Outputs (4)

Genome-wide association studies in asthma (2016)
Journal Article
Portelli, M. A., & Sayers, I. (in press). Genome-wide association studies in asthma. https://doi.org/10.1002/9780470015902.a0024639

Asthma is a complex respiratory disease, with both genetic and environmental factors contributing to disease susceptibility. Genome-wide association studies (GWAS) have now identified novel risk alleles and loci associated with asthma diagnosis and m... Read More about Genome-wide association studies in asthma.

Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identi?es a severe, nonatopic subset of patients (2016)
Journal Article
Portelli, M. A., Moseley, C., Stewart, C. E., Postma, D. S., Howarth, P., Warner, J., …Sayers, I. (in press). Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients. Allergy, https://doi.org/10.1111/all.13046

Rationale: Genetic polymorphisms in the asthma susceptibility gene, urokinase plasminogen activator receptor (uPAR/PLAUR) have been associated with lung function decline and uPAR blood levels in asthma subjects. Preliminary studieshave identi?ed uPAR... Read More about Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identi?es a severe, nonatopic subset of patients.

Erratum: Letters to the editor: Genetic polymorphism and soluble urokinase plasminogen activator receptor (2016)
Journal Article
Sayers, I., Portelli, M. A., & Siedlinski, M. (2016). Erratum: Letters to the editor: Genetic polymorphism and soluble urokinase plasminogen activator receptor. FASEB Journal, 30(6), 2451. https://doi.org/10.1096/fj.15-1201LTERERR

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma (2016)
Journal Article
Ierodiakonou, D., Portelli, M. A., Postma, D. S., Koppelman, G. H., Gerritsen, J., ten Hacken, N. H., …Sayers, I. (2016). Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma. European Respiratory Journal, 47(5), https://doi.org/10.1183/13993003.01571-2015