Skip to main content

Research Repository

Advanced Search

All Outputs (10)

The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink (2016)
Journal Article
Pearce, F. A., Grainge, M. J., Lanyon, P. C., Watts, R. A., & Hubbard, R. B. (in press). The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink. Rheumatology, https://doi.org/10.1093/rheumatology/kew413

Objectives: To estimate the incidence, prevalence and mortality of Granulomatosis with polyangiitis (GPA) in the United Kingdom. Methods: We conducted a historical cohort study using data from the Clinical Practice Research Datalink and Hospital Epi... Read More about The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink.

Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study (2016)
Journal Article
Sultan, A. A., West, J., Grainge, M. J., Riley, R. D., Tata, L. J., Stephansson, O., …Ludvigsson, J. F. (2016). Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ, 355(i6253), https://doi.org/10.1136/bmj.i6253

Objective: To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum). Design: Cohort study. Setting: Records from England based Clinical Practice Research Datalink (CPRD)... Read More about Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study.

Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families (2016)
Journal Article
Chou, I., Kuo, C., Huang, Y., Grainge, M. J., Valdes, A. M., See, L., …Doherty, M. (in press). Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families. Schizophrenia Bulletin, https://doi.org/10.1093/schbul/sbw159

Strong familial aggregation of schizophrenia has been reported but there is uncertainty concerning the degree of genetic contribution to the phenotypic variance of the disease. This study aimed to examine the familial aggregation and heritability of... Read More about Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families.

Early clinical features in Systemic Lupus Erythematosus: can they be used to achieve earlier diagnosis?: a risk prediction model (2016)
Journal Article
Rees, F., Doherty, M., Lanyon, P., Davenport, G., Riley, R. D., Zhang, W., & Grainge, M. J. (2017). Early clinical features in Systemic Lupus Erythematosus: can they be used to achieve earlier diagnosis?: a risk prediction model. Arthritis Care and Research, 69(6), 833-841. https://doi.org/10.1002/acr.23021

OBJECTIVES: 1) To compare the primary care consulting behaviour prior to diagnosis of people with Systemic Lupus Erythematosus (SLE) with controls, 2) to develop and validate a risk prediction model to aid earlier SLE diagnosis. METHODS: 1,739 in... Read More about Early clinical features in Systemic Lupus Erythematosus: can they be used to achieve earlier diagnosis?: a risk prediction model.

Risk of venous thromboembolism in hospitalised cancer patients in England – A cohort study (2016)
Journal Article
Ratib, S., Walker, A. J., Card, T. R., & Grainge, M. J. (2016). Risk of venous thromboembolism in hospitalised cancer patients in England – A cohort study. Journal of Hematology and Oncology, 9, Article 60. https://doi.org/10.1186/s13045-016-0291-0

Background: Venous thromboembolism (VTE) is a well-recognised and life-threatening complication in patients with cancer. However, the precise risk of VTE in hospitalised cancer patients in England has not been previously reported. Methods: We condu... Read More about Risk of venous thromboembolism in hospitalised cancer patients in England – A cohort study.

Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population (2016)
Journal Article
Pearce, F. A., Lanyon, P. C., Grainge, M. J., Shaunak, R., Mahr, A., Hubbard, R. B., & Watts, R. A. (in press). Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population. Rheumatology, 55(9), https://doi.org/10.1093/rheumatology/kew232

Objectives: We aimed to estimate the incidence of ANCA-associated vasculitis in the UK and how this varied by ethnic group. Methods: We identified incident cases of ANCA-associated vasculitis between March 2007 and June 2013 in the Nottingham–Derby... Read More about Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population.

Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data (2016)
Journal Article
Walker, A. J., Baldwin, D. R., Card, T. R., Powell, H. A., Hubbard, R. B., & Grainge, M. J. (in press). Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data. British Journal of Cancer, 115(1), https://doi.org/10.1038/bjc.2016.143

Background: Venous thromboembolism is a potentially preventable cause of death in people with lung cancer. Identification of those most at risk and high risk periods may provide the opportunity for better targeted intervention. Methods: We conduc... Read More about Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data.

Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012 (2016)
Journal Article
Rees, F., Doherty, M., Grainge, M., Lanyon, P., Davenport, G., & Zhang, W. (in press). Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012. Arthritis Care and Research, 68(6), https://doi.org/10.1002/acr.22751

Objective: To estimate the comorbidity associated with systemic lupus erythematosus (SLE) in the UK during 1999–2012. Methods: A retrospective cohort study using the UK Clinical Practice Research Datalink was conducted. Prevalent cases of SLE wer... Read More about Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012.

Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012 (2016)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Lanyon, P., Davenport, G., & Zhang, W. (2016). Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012. Rheumatology, 55(5), 854-860. https://doi.org/10.1093/rheumatology/kev424

OBJECTIVES: To estimate the mortality associated with SLE during the period 1999-2012 by age, gender and region; and to ascertain the cause of death for people with SLE. METHODS: A retrospective cohort study using the UK Clinical Practice Research... Read More about Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012.