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Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro (2016)
Journal Article
Woodham, A. W., Sanna, A. M., Taylor, J. R., Skeate, J. G., Da Silva, D. M., Dekker, L. V., & Kast, W. M. (2016). Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro. Virology Journal, 13(1), 1-5. https://doi.org/10.1186/s12985-016-0649-5

© 2016 The Author(s). During sexual transmission of human immunodeficiency virus (HIV), macrophages are initial targets for HIV infection. Secretory leukocyte protease inhibitor (SLPI) has been shown to protect against HIV infection of macrophages th... Read More about Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro.

Alkylation of staurosporine to derive a kinase probe for fluorescence applications (2016)
Journal Article
Disney, A. J., Kellam, B., & Dekker, L. V. (in press). Alkylation of staurosporine to derive a kinase probe for fluorescence applications. ChemMedChem, 11, https://doi.org/10.1002/cmdc.201500589

The natural product staurosporine is a high-affinity inhibitor of nearly all mammalian protein kinases.The labelling of staurosporine has proven effective as a means of generating protein kinase research tools. Most tools have been generated by acyla... Read More about Alkylation of staurosporine to derive a kinase probe for fluorescence applications.