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On the combined effects of normobaric hypoxia and bed rest upon bone and mineral metabolism: Results from the PlanHab study (2016)
Journal Article
Rittweger, J., Debevec, T., Frings-Meuthen, P., Lau, P., Mittag, U., Ganse, B., …Mekjavic, I. B. (2016). On the combined effects of normobaric hypoxia and bed rest upon bone and mineral metabolism: Results from the PlanHab study. BONE, 91, 130-138. https://doi.org/10.1016/j.bone.2016.07.013

Bone losses are common as a consequence of unloading and also in patients with chronic obstructive pulmonary disease (COPD). Although hypoxia has been implicated as an important factor to drive bone loss, its interaction with unloading remains unreso... Read More about On the combined effects of normobaric hypoxia and bed rest upon bone and mineral metabolism: Results from the PlanHab study.

Effects of prolonged hypoxia and bed rest on appetite and appetite-related hormones (2016)
Journal Article
Debevec, T., Simpson, E. J., Mekjavic, I. B., Eiken, O., & Macdonald, I. A. (2016). Effects of prolonged hypoxia and bed rest on appetite and appetite-related hormones. Appetite, 107, 28-37. https://doi.org/10.1016/j.appet.2016.07.005

Environmental hypoxia and inactivity have both been shown to modulate appetite. To elucidate the independent and combined effects of hypoxia and bed rest-induced inactivity on appetite-related hormones and subjective appetite, eleven healthy, non-obe... Read More about Effects of prolonged hypoxia and bed rest on appetite and appetite-related hormones.

The Effect of Normobaric Hypoxic Confinement on Metabolism, Gut Hormones, and Body Composition (2016)
Journal Article
Mekjavic, I. B., Amon, M., Kölegård, R., Kounalakis, S. N., Simpson, L., Eiken, O., …Macdonald, I. A. (2016). The Effect of Normobaric Hypoxic Confinement on Metabolism, Gut Hormones, and Body Composition. Frontiers in Physiology, 7, Article 202. https://doi.org/10.3389/fphys.2016.00202

To assess the effect of normobaric hypoxia on metabolism, gut hormones, and body composition, 11 normal weight, aerobically trained (O2peak: 60.6 ± 9.5 ml·kg-1·min-1) men (73.0 ± 7.7 kg; 23.7 ± 4.0 years, BMI 22.2 ± 2.4 kg·m-2) were confined to a nor... Read More about The Effect of Normobaric Hypoxic Confinement on Metabolism, Gut Hormones, and Body Composition.

Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome; a randomised, controlled trial in an at-risk population (2016)
Journal Article
Simpson, E. J., Mendis, B., & MacDonald, I. A. (in press). Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome; a randomised, controlled trial in an at-risk population. Food and Function, 7(4), https://doi.org/10.1039/C6FO00039H

Data from epidemiological and in vitro studies suggest that orange juice (OJ) may have a positive impact on lipid metabolism. However, there have been reports in the media claiming detrimental consequences of 100% juice consumption, including weight-... Read More about Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome; a randomised, controlled trial in an at-risk population.

PlanHab: the combined and separate effects of 16 days of bed rest and normobaric hypoxic confinement on circulating lipids and indices of insulin sensitivity in healthy men (2016)
Journal Article
Simpson, E. J., Debevec, T., Eiken, O., Mekjavic, I., & Macdonald, I. (2016). PlanHab: the combined and separate effects of 16 days of bed rest and normobaric hypoxic confinement on circulating lipids and indices of insulin sensitivity in healthy men. Journal of Applied Physiology, 120(8), 947-955. doi:10.1152/japplphysiol.00897.2015