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All Outputs (9)

Acetylcholinesterase activity measurement and clinical features of delirium (2016)
Journal Article
Jackson, T., Moorey, H., Sheehan, B., Maclullich, A., Gladman, J., & Lord, J. (2017). Acetylcholinesterase activity measurement and clinical features of delirium. Dementia and Geriatric Cognitive Disorders, 43(1-2), https://doi.org/10.1159/000452832

Aims: Cholinergic deficiency is commonly implicated in the pathophysiology of delirium. We aimed to investigate the relationship between directly measured serum AChE activity and (1) clinical features of delirium and (2) outcomes, among older hospita... Read More about Acetylcholinesterase activity measurement and clinical features of delirium.

New horizons: the management of hypertension in people with dementia (2016)
Journal Article
Harrison, J. K., Van Der Wardt, V., Conroy, S. P., Stott, D. J., Dening, T., Gordon, A. L., …Gladman, J. R. (2016). New horizons: the management of hypertension in people with dementia. Age and Ageing, 45(6), 740-746. https://doi.org/10.1093/ageing/afw155

The optimal management of hypertension in people with dementia is uncertain. This review explores if people with dementia experience greater adverse effects from antihypertensive medications, if cognitive function is protected or worsened by controll... Read More about New horizons: the management of hypertension in people with dementia.

Effective health care for older people living and dying in care homes: a realist review (2016)
Journal Article
Goodman, C., Dening, T., Gordon, A. L., Davies, S. L., Meyer, J., Martin, F. C., …Zubair, M. (in press). Effective health care for older people living and dying in care homes: a realist review. BMC Health Services Research, 16(269), https://doi.org/10.1186/s12913-016-1493-4

Background: Care home residents in England have variable access to health care services. There is currently no coherent policy or consensus about the best arrangements to meet these needs. The purpose of this review was to explore the evidence for ho... Read More about Effective health care for older people living and dying in care homes: a realist review.

Qualitative study investigating the commissioning process for older people's services provided by third sector organisations: SOPRANO study protocol (2016)
Journal Article
Sands, G., Chadborn, N., Craig, C., & Gladman, J. R. (2016). Qualitative study investigating the commissioning process for older people's services provided by third sector organisations: SOPRANO study protocol. BMJ Open, 6(5), Article e010724. https://doi.org/10.1136/bmjopen-2015-010724

Introduction The commissioning of third sector services for older people may influence the quality, availability and coordination of services for older people. The SOPRANO study aims to understand the relationships between and processes of commissio... Read More about Qualitative study investigating the commissioning process for older people's services provided by third sector organisations: SOPRANO study protocol.

Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study. (2016)
Journal Article
Jackson, T. A., MacLullich, A., Gladman, J. F., Lord, J. M., & Sheehan, B. (2016). Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study. Age and Ageing, 45(4), 493–499. https://doi.org/10.1093/ageing/afw064

Background: delirium and dementia are common in the general hospital, being present in nearly 50% of older unselected admissions to hospital. Cognitive impairment is a risk factor for delirium, but the prevalence of previously undiagnosed cognitive i... Read More about Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study..

Diagnostic test accuracy of informant based tools to diagnose dementia in older hospital patients with delirium (2016)
Journal Article
Jackson, T. A., MacLullich, A., Gladman, J. R., Lord, J. M., & Sheehan, B. (2016). Diagnostic test accuracy of informant based tools to diagnose dementia in older hospital patients with delirium. Age and Ageing, 45(4), 505-511. doi:10.1093/ageing/afw065

Background: delirium and dementia co-exist commonly in hospital. Older people with delirium have high rates of undiagnosed dementia, but delirium affects the use of cognitive testing in dementia diagnosis. Novel methods to detect dementia in delirium... Read More about Diagnostic test accuracy of informant based tools to diagnose dementia in older hospital patients with delirium.

Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability (2016)
Journal Article
Conroy, S. P., Harrison, J. K., van der Wardt, V., Harwood, R. H., Logan, P., Welsh, T., & Gladman, J. R. (2016). Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability. Age and Ageing, 45(4), 456-462. https://doi.org/10.1093/ageing/afw050

BACKGROUND: Ambulatory blood pressure monitoring (ABPM) may be helpful for the management of hypertension, but little is known about its tolerability in people with dementia. OBJECTIVE: To review the published evidence to determine the tolerabil... Read More about Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability.

New horizons in the implementation and research of comprehensive geriatric assessment: knowing, doing and the “know-do” gap (2016)
Journal Article
Gladman, J. R., Conroy, S. P., Ranhoff, A. H., & Gordon, A. L. (2016). New horizons in the implementation and research of comprehensive geriatric assessment: knowing, doing and the “know-do” gap. Age and Ageing, 45(2), 194-200. https://doi.org/10.1093/ageing/afw012

In this paper we outline the relationship between the need to put existing applied health research knowledge into practice (the “know-do gap”) and the need to improve the evidence base (the “know gap”) with respect to the health care process used for... Read More about New horizons in the implementation and research of comprehensive geriatric assessment: knowing, doing and the “know-do” gap.

Comprehensive geriatric assessment on an acute medical unit: a qualitative study of older people’s and informal carer’s perspectives of the care and treatment received (2016)
Journal Article
Darby, J., Williamson, T., Logan, P., & Gladman, J. R. (2016). Comprehensive geriatric assessment on an acute medical unit: a qualitative study of older people’s and informal carer’s perspectives of the care and treatment received. Clinical Rehabilitation, 31(1), https://doi.org/10.1177/0269215515624134

Objective: This qualitative study was imbedded in a randomised controlled trial evaluating the addition of geriatricians to usual care to enable the comprehensive geriatric assessment process with older patients on acute medical units. The qualitativ... Read More about Comprehensive geriatric assessment on an acute medical unit: a qualitative study of older people’s and informal carer’s perspectives of the care and treatment received.